The Effect of Buddleja officinalis Maxim Eye Drops on Morphology and Apoptosis in Lacrimal Gland of Experimental Dry Eye Rabbit Model
Joint Authors
Peng, Qinghua
Yang, Yi Jing
Peng, Jun
Zhou, Yasha
Qin, Genyan
Zhang, Youwei
Peng, Xiaofang
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-02-05
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
The purpose of this study was to investigate the effects of Buddleja officinalis Maxim eye drops on morphology and apoptosis in lacrimal glands of the experimental dry eye rabbit model.
A total of thirty-six male rabbits were divided into six study groups, consisting of the control group and the dry eye rabbit model group (without any treatment), the dry eye rabbit model group treated with testosterone, and the dry eye rabbit model group treated with different concentrations of Buddleja officinalis Maxim eye drops (1.0 mg/ml, 1.5 mg/ml and 3.0 mg/ml).
The lacrimal glands were evaluated by hematoxylin-eosin staining and immunohistochemistry.
Buddleja officinalis Maxim eye drops can improve the morphological structure of the lacrimal gland in the dry eye model of castrated rabbits.
The average optical density values of PI3K, Akt, and caspase-9 protein in the lacrimal gland tissue of the 3 mg/ml Buddleja officinalis Maxim eye drops group were significantly different from those in the model group (P<0.01) and similar to the testosterone control group and the control group (P>0.05).
Buddleja officinalis Maxim eye drops can improve the morphological structure of the lacrimal gland in the dry eye model of castrated rabbits.
American Psychological Association (APA)
Qin, Genyan& Zhou, Yasha& Peng, Jun& Zhang, Youwei& Peng, Xiaofang& Peng, Qinghua…[et al.]. 2019. The Effect of Buddleja officinalis Maxim Eye Drops on Morphology and Apoptosis in Lacrimal Gland of Experimental Dry Eye Rabbit Model. Journal of Ophthalmology،Vol. 2019, no. 2019, pp.1-7.
https://search.emarefa.net/detail/BIM-1185882
Modern Language Association (MLA)
Qin, Genyan…[et al.]. The Effect of Buddleja officinalis Maxim Eye Drops on Morphology and Apoptosis in Lacrimal Gland of Experimental Dry Eye Rabbit Model. Journal of Ophthalmology No. 2019 (2019), pp.1-7.
https://search.emarefa.net/detail/BIM-1185882
American Medical Association (AMA)
Qin, Genyan& Zhou, Yasha& Peng, Jun& Zhang, Youwei& Peng, Xiaofang& Peng, Qinghua…[et al.]. The Effect of Buddleja officinalis Maxim Eye Drops on Morphology and Apoptosis in Lacrimal Gland of Experimental Dry Eye Rabbit Model. Journal of Ophthalmology. 2019. Vol. 2019, no. 2019, pp.1-7.
https://search.emarefa.net/detail/BIM-1185882
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1185882
