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Submacular Injection of Ranibizumab as a New Surgical Treatment for Refractory Diabetic Macular Edema
Joint Authors
Abdel Hadi, Ahmed M.
Elbaha, Samir Mohamed
Abouhussein, Mahmoud A.
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-10-21
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Purpose.
In this study, we describe a new surgical technique for the treatment of refractory DME.
The technique consists of vitrectomy with ILM peeling with a subretinal injection of ranibizumab.
Methods.
This is a prospective interventional noncomparative study including patients with refractory DME.
Included patients were subjected to the new surgical technique of pars plana vitrectomy with subretinal injection of ranibizumab.
Results.
The study included 19 eyes with refractory macular edema, in which this novel technique was attempted.
There were 10 males and 9 females.
The age of the patients ranged from 17 to 67 years with a mean of 55.58 ± 13.242 years.
The duration of diabetes before enrollment in the study ranged from 7 to 25 years with a mean of 16.3 years.
Preoperatively, the mean CMT of the eyes ranged from 352 to 883 microns with mean ± SD of 498.58 ± 152.16 microns.
Postoperatively, this improved significantly to 373.5 ± 100.3, 355.9 ± 89.8, and 365.74 ± 120.12 microns at 1, 3, and 6 months, respectively (p≤0.001 for all).
Conclusion.
This novel surgical procedure of vitrectomy with ILM peeling with a subretinal injection of ranibizumab is effective in cases of refractory DME.
The study has been registered in Contact ClinicalTrials.gov PRS Identifier: NCT03975088.
American Psychological Association (APA)
Elbaha, Samir Mohamed& Abdel Hadi, Ahmed M.& Abouhussein, Mahmoud A.. 2019. Submacular Injection of Ranibizumab as a New Surgical Treatment for Refractory Diabetic Macular Edema. Journal of Ophthalmology،Vol. 2019, no. 2019, pp.1-5.
https://search.emarefa.net/detail/BIM-1185974
Modern Language Association (MLA)
Elbaha, Samir Mohamed…[et al.]. Submacular Injection of Ranibizumab as a New Surgical Treatment for Refractory Diabetic Macular Edema. Journal of Ophthalmology No. 2019 (2019), pp.1-5.
https://search.emarefa.net/detail/BIM-1185974
American Medical Association (AMA)
Elbaha, Samir Mohamed& Abdel Hadi, Ahmed M.& Abouhussein, Mahmoud A.. Submacular Injection of Ranibizumab as a New Surgical Treatment for Refractory Diabetic Macular Edema. Journal of Ophthalmology. 2019. Vol. 2019, no. 2019, pp.1-5.
https://search.emarefa.net/detail/BIM-1185974
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1185974