Corneal Endothelial Cell Density and Morphology in Healthy Egyptian Eyes
Joint Authors
Farouk, Mahmoud Mohamed
Sayed, Khulood Mohammed
Mohamed Mostafa, Engy
Anbar, Mohamed
Ammar, Hatem
Hassan, Alahmady Hamad Alsmman
Abdellah, Marwa Mahmoud
Elghobaier, Mohamed Gamal
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-02-24
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Purpose.
To evaluate the corneal endothelial cell density and morphology in normal Egyptian eyes.
Methods.
In total, 568 healthy eyes of 568 Egyptian volunteers aged 20 to 85 years were examined using noncontact specular microscopy for the central corneal thickness (CCT), mean endothelial cell density (MCD), coefficient of variation (CV) in cell area, mean cell area (MCA), and hexagonal cell (Hex) percentage.
Variables were compared between sexes and between different age groups.
Results.
The mean CCT, MCD, and MCA were 514.45 ± 43.04 μm, 2647.50 ± 382.62 cells/mm2, and 390.59 ± 149.94 μm2, respectively.
MCD and MCA showed no significant differences between men and women (P=0.171 and 0.099, respectively), whereas CV (%) and Hex (%) showed significant differences (P=0.024 and 0.015, respectively).
CCT (P=0.007, r = −0.113) and MCD (P<0.001, r = −0.357) exhibited a significant negative correlation with age, whereas CV (%) (P<0.001, r = 0.341) and MCA (P=0.008, r = 0.111) exhibited a significant positive correlation.
The mean rate of endothelial cell loss from 20 to 85 years of age was 0.3% per year.
Conclusions.
Our results provide normative data for the corneal endothelium in healthy Egyptian eyes, thus increasing the knowledge base for corneal endothelial cell parameters in healthy Egyptian eyes.
Furthermore, our findings can be used as baseline values for comparisons between Egyptian and other populations and for studies of the endothelial cell reserve and capacity for intraocular surgery and corneal transplantation.
American Psychological Association (APA)
Abdellah, Marwa Mahmoud& Ammar, Hatem& Anbar, Mohamed& Mohamed Mostafa, Engy& Farouk, Mahmoud Mohamed& Sayed, Khulood Mohammed…[et al.]. 2019. Corneal Endothelial Cell Density and Morphology in Healthy Egyptian Eyes. Journal of Ophthalmology،Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1186000
Modern Language Association (MLA)
Abdellah, Marwa Mahmoud…[et al.]. Corneal Endothelial Cell Density and Morphology in Healthy Egyptian Eyes. Journal of Ophthalmology No. 2019 (2019), pp.1-8.
https://search.emarefa.net/detail/BIM-1186000
American Medical Association (AMA)
Abdellah, Marwa Mahmoud& Ammar, Hatem& Anbar, Mohamed& Mohamed Mostafa, Engy& Farouk, Mahmoud Mohamed& Sayed, Khulood Mohammed…[et al.]. Corneal Endothelial Cell Density and Morphology in Healthy Egyptian Eyes. Journal of Ophthalmology. 2019. Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1186000
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1186000