Retinal Vasculature and Microstructure in Early Dry-Type Myopic Maculopathy
Joint Authors
Wang, Yanling
Sun, Jiao
Wang, Jialin
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-08-05
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Purpose.
The aim of this cross-sectional study was to characterize and compare the retinal vasculature and microstructure in patients with early dry-type myopic maculopathy.
Methods.
Patients with a refractive error of less than −6 diopters were enrolled and classified into two groups.
Group 1 comprised 82 eyes with a tessellated fundus, and group 2 comprised 56 eyes with diffuse chorioretinal atrophy (DCA).
The clinical characteristics, refractive error, axial length, retinal vessel density of the superficial capillary plexus (SCP) and deep capillary plexus (DCP), macular choroidal thickness, and best-corrected visual acuity (BCVA), were compared between the groups.
Logistic regression was used to determine the protective and risk factors for DCA.
Results.
Group 1 patients were significantly younger and had better BCVA, less myopia, and shorter axial length than group 2 patients.
The vessel densities of the SCP and DCP, choroidal thickness, retinal nerve fiber layer thickness, ganglion cell complex thickness, and retinal thickness were reduced in group 2.
Multiple logistic regression analysis revealed that the vessel densities of the SCP and DCP were protective factors for DCA.
Conclusions.
The vessel density of the SCP had the highest diagnostic value (sensitivity = 78.0% and specificity = 96.6%).
When the SCP vessel density was reduced to ≤49.98%, DCA was indicated.
The retinal vessel densities of the SCP and DCP and parameters of the microstructure were reduced significantly in patients with DCA.
Vessel density may be a better diagnostic indicator of the development of DCA.
American Psychological Association (APA)
Sun, Jiao& Wang, Jialin& Wang, Yanling. 2019. Retinal Vasculature and Microstructure in Early Dry-Type Myopic Maculopathy. Journal of Ophthalmology،Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1186142
Modern Language Association (MLA)
Sun, Jiao…[et al.]. Retinal Vasculature and Microstructure in Early Dry-Type Myopic Maculopathy. Journal of Ophthalmology No. 2019 (2019), pp.1-8.
https://search.emarefa.net/detail/BIM-1186142
American Medical Association (AMA)
Sun, Jiao& Wang, Jialin& Wang, Yanling. Retinal Vasculature and Microstructure in Early Dry-Type Myopic Maculopathy. Journal of Ophthalmology. 2019. Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1186142
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1186142