Dynamic Rule-Based Algorithm to Tune Insulin-on-Board Constraints for a Hybrid Artificial Pancreas System
Joint Authors
Bertachi, Arthur
Biagi, Lyvia
Beneyto, Aleix
Vehí, Josep
Source
Journal of Healthcare Engineering
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-01-11
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
The artificial pancreas (AP) is a system intended to control blood glucose levels through automated insulin infusion, reducing the burden of subjects with type 1 diabetes to manage their condition.
To increase patients’ safety, some systems limit the allowed amount of insulin active in the body, known as insulin-on-board (IOB).
The safety auxiliary feedback element (SAFE) layer has been designed previously to avoid overreaction of the controller and thus avoiding hypoglycemia.
In this work, a new method, so-called “dynamic rule-based algorithm,” is presented in order to adjust the limits of IOB in real time.
The algorithm is an extension of a previously designed method which aimed to adjust the limits of IOB for a meal with 60 grams of carbohydrates (CHO).
The proposed method is intended to be applied on hybrid AP systems during 24 h operation.
It has been designed by combining two different strategies to set IOB limits for different situations: (1) fasting periods and (2) postprandial periods, regardless of the size of the meal.
The UVa/Padova simulator is considered to assess the performance of the method, considering challenging scenarios.
In silico results showed that the method is able to reduce the time spent in hypoglycemic range, improving patients’ safety, which reveals the feasibility of the approach to be included in different control algorithms.
American Psychological Association (APA)
Bertachi, Arthur& Biagi, Lyvia& Beneyto, Aleix& Vehí, Josep. 2020. Dynamic Rule-Based Algorithm to Tune Insulin-on-Board Constraints for a Hybrid Artificial Pancreas System. Journal of Healthcare Engineering،Vol. 2020, no. 2020, pp.1-11.
https://search.emarefa.net/detail/BIM-1186197
Modern Language Association (MLA)
Bertachi, Arthur…[et al.]. Dynamic Rule-Based Algorithm to Tune Insulin-on-Board Constraints for a Hybrid Artificial Pancreas System. Journal of Healthcare Engineering No. 2020 (2020), pp.1-11.
https://search.emarefa.net/detail/BIM-1186197
American Medical Association (AMA)
Bertachi, Arthur& Biagi, Lyvia& Beneyto, Aleix& Vehí, Josep. Dynamic Rule-Based Algorithm to Tune Insulin-on-Board Constraints for a Hybrid Artificial Pancreas System. Journal of Healthcare Engineering. 2020. Vol. 2020, no. 2020, pp.1-11.
https://search.emarefa.net/detail/BIM-1186197
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1186197