Research on Multi-Time-Delay Gene Regulation Network Based on Fuzzy Label Propagation
Joint Authors
Zhang, Qian
Li, Haigang
Li, Ming
Source
Journal of Healthcare Engineering
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-03-11
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
In view of time delay existing in gene regulation, by using the analysis idea and methods of complex network, this paper proposes a multi-time-delay gene regulation network analysis method based on the fuzzy label propagation.
The algorithm takes the relative change trend coefficient, the correlation coefficient, and the mutual information as the similarity measurement indexes for the gene pair, fully reflecting the correlation of gene pairs and simultaneously obtaining the gene regulation relationship and the time delay through the fuzzy label propagation algorithm of the semisupervised learning.
Experimental results of the cell cycle-regulated genes of yeast show that the proposed construction method of GRN can not only correctly select potential regulation genes but also provide details about the gene regulator model, thereby more accurately constructing gene regulation network.
American Psychological Association (APA)
Li, Haigang& Zhang, Qian& Li, Ming. 2020. Research on Multi-Time-Delay Gene Regulation Network Based on Fuzzy Label Propagation. Journal of Healthcare Engineering،Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1186222
Modern Language Association (MLA)
Li, Haigang…[et al.]. Research on Multi-Time-Delay Gene Regulation Network Based on Fuzzy Label Propagation. Journal of Healthcare Engineering No. 2020 (2020), pp.1-8.
https://search.emarefa.net/detail/BIM-1186222
American Medical Association (AMA)
Li, Haigang& Zhang, Qian& Li, Ming. Research on Multi-Time-Delay Gene Regulation Network Based on Fuzzy Label Propagation. Journal of Healthcare Engineering. 2020. Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1186222
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1186222