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The Effects of Diabetic Duration on Lacrimal Functional Unit in Patients with Type II Diabetes
Joint Authors
Lu, Xiaoxiao
Zhang, Yan
Zeng, Xiaoyu
Lv, Ying
Gu, Zhongxiu
Jia, Zhe
Zhang, Chen
Chu, Chenchen
Gao, Yichen
Nie, Yu
Wang, Yanxia
Zhao, Shaozhen
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-01-10
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Purpose.
To observe ocular surface changes in Type II diabetic patients with different disease durations and to understand the correlations between clinical parameters and diabetic durations.
Methods.
In this cross-sectional, prospective study, 51 healthy controls and 91 patients with Type II diabetes were enrolled.
The diabetics were divided into 3 subgroups according to the disease duration, including duration <10 y group, 10 to 20 y group, and ≥21 y group.
All subjects underwent clinical ocular examinations, including lipid layer thickness (LLT), blinking rate, tear meniscus height (TMH), noninvasive tear film break-up time (NI-BUT), meibography, superficial punctate keratopathy (SPK) scoring, corneal sensitivity, and Schirmer I test.
They were also evaluated using the standard patient evaluation of eye dryness (SPEED) questionnaire.
Results.
SPEED score, meiboscore, SPK score, LLT, Schirmer I test, and corneal sensitivity differed significantly between the diabetic and healthy control groups.
Further, SPEED score, Schirmer I test, corneal sensitivity, meiboscore, and blink rate significantly differed among the 3 diabetic subgroups and the control group.
In diabetics, the SPEED score correlated with the SPK score, blink rate, TMH, and LLT; NI-BUT with TMH, LLT, and blink rate; TMH with the SPK score; Schirmer I test with the SPK score; and corneal sensitivity with the meiboscore.
More importantly, the Schirmer I test, corneal sensitivity, and SPEED score negatively correlated with diabetic duration.
Conclusion.
Diabetic duration is an important factor that affects functions of the lacrimal functional unit in patients with Type II diabetes.
The trends of changes in the ocular parameters vary along the course of diabetes.
American Psychological Association (APA)
Zeng, Xiaoyu& Lv, Ying& Gu, Zhongxiu& Jia, Zhe& Zhang, Chen& Lu, Xiaoxiao…[et al.]. 2019. The Effects of Diabetic Duration on Lacrimal Functional Unit in Patients with Type II Diabetes. Journal of Ophthalmology،Vol. 2019, no. 2019, pp.1-11.
https://search.emarefa.net/detail/BIM-1186257
Modern Language Association (MLA)
Zeng, Xiaoyu…[et al.]. The Effects of Diabetic Duration on Lacrimal Functional Unit in Patients with Type II Diabetes. Journal of Ophthalmology No. 2019 (2019), pp.1-11.
https://search.emarefa.net/detail/BIM-1186257
American Medical Association (AMA)
Zeng, Xiaoyu& Lv, Ying& Gu, Zhongxiu& Jia, Zhe& Zhang, Chen& Lu, Xiaoxiao…[et al.]. The Effects of Diabetic Duration on Lacrimal Functional Unit in Patients with Type II Diabetes. Journal of Ophthalmology. 2019. Vol. 2019, no. 2019, pp.1-11.
https://search.emarefa.net/detail/BIM-1186257
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1186257