10-Year Results of Standard Cross-Linking in Patients with Progressive Keratoconus in Romania
Joint Authors
Nicula, Cristina
Pop, Radu
Rednik, Anca
Nicula, Dorin
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-03-07
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Purpose.
The purpose of the current study was to evaluate the long-term functional results based on keratometric measurements, spherical and cylinder equivalent in patients with progressive keratoconus treated with conventional “epi-off” corneal collagen cross-linking (CXL).
Methods.
We conducted a retrospective study in which 113 eyes from 90 keratoconus-treated patients with CXL between 2006 and 2008 in Oculens Eye Clinic from Cluj-Napoca, Romania, were included.
The diagnosis of keratoconus was based on corneal topography and its clinical signs.
All patients were evaluated preoperatively, and a follow-up was performed at 1, 3, and 6 months and every year from 1 to 10 years after conventional CXL.
Results.
All keratometry measurements improved significantly during the follow-up.
Compared to preoperative values, the improvement of Kmax become statistically significant at 1 year after CXL (mean change compared to baseline −0.9 D, p<0.001) and remained statistically significant thereafter up to 10 years (mean change compared to baseline −2.3 D, p<0.001).
As compared to preoperative values, mean spherical equivalent and mean cylinder improved during the follow-up, from a mean of −6.22 D before CXL to a mean value of −5.0 at 10 years, following CXL for spherical equivalent and from −4.4 D at baseline to −3.4 D at 10 years for cylinder (p<0.05 for both).
Uncorrected visual acuity increased, remaining statistically significant, by 0.104 logMAR at 10 years after CXL (p=0.0015), and best-corrected visual acuity increased by 0.135 logMAR at 10 years after CXL (p=0.015).
We did not observe any case of severe complication.
Conclusion.
Our results show that CXL has a favorable effect on the progression of KC.
The reduced K values, cylinder and spherical equivalent, and increased visual acuity remained the same 10 years after the procedure.
American Psychological Association (APA)
Nicula, Cristina& Pop, Radu& Rednik, Anca& Nicula, Dorin. 2019. 10-Year Results of Standard Cross-Linking in Patients with Progressive Keratoconus in Romania. Journal of Ophthalmology،Vol. 2019, no. 2019, pp.1-5.
https://search.emarefa.net/detail/BIM-1186286
Modern Language Association (MLA)
Nicula, Cristina…[et al.]. 10-Year Results of Standard Cross-Linking in Patients with Progressive Keratoconus in Romania. Journal of Ophthalmology No. 2019 (2019), pp.1-5.
https://search.emarefa.net/detail/BIM-1186286
American Medical Association (AMA)
Nicula, Cristina& Pop, Radu& Rednik, Anca& Nicula, Dorin. 10-Year Results of Standard Cross-Linking in Patients with Progressive Keratoconus in Romania. Journal of Ophthalmology. 2019. Vol. 2019, no. 2019, pp.1-5.
https://search.emarefa.net/detail/BIM-1186286
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1186286