Toward Respiratory Support of Critically Ill COVID-19 Patients Using Repurposed Kidney Hollow Fiber Membrane Dialysers to Oxygenate the Blood
Joint Authors
Rubin, David M.
Stacey, Neil T.
Matambo, Tonderayi
Vale, Claudia Do
Sussman, Martin J.
Snyman, Tracy
Mer, Mervyn
Hildebrandt, Diane
Source
Journal of Healthcare Engineering
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-11-03
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
The COVID-19 pandemic has highlighted resource constraints in respiratory support.
The oxygen transfer characteristics of a specific hollow fiber membrane dialyser was investigated with a view to repurposing the device as a low-cost, readily available blood oxygenator.
Oxygen transfer in a low-flux hollow fiber dialyser with a polysulfone membrane was studied by passing first water and then blood through the dialyser in countercurrent to high-purity oxygen.
Oxygen transfer rates of about 15% of the nominal 250 ml (STP)/min of a typical adult oxygen consumption rate were achieved for blood flow rates of 500 ml/min.
Using two such dialysis devices in parallel could provide up to 30% of the nominal oxygen consumption.
Specific hollow fiber dialysis devices operating with suitable pumps in a veno-venous access configuration could provide a cost-effective and readily available supplementation of respiratory support in the face of severe resource constraints.
American Psychological Association (APA)
Rubin, David M.& Stacey, Neil T.& Matambo, Tonderayi& Vale, Claudia Do& Sussman, Martin J.& Snyman, Tracy…[et al.]. 2020. Toward Respiratory Support of Critically Ill COVID-19 Patients Using Repurposed Kidney Hollow Fiber Membrane Dialysers to Oxygenate the Blood. Journal of Healthcare Engineering،Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1186566
Modern Language Association (MLA)
Rubin, David M.…[et al.]. Toward Respiratory Support of Critically Ill COVID-19 Patients Using Repurposed Kidney Hollow Fiber Membrane Dialysers to Oxygenate the Blood. Journal of Healthcare Engineering No. 2020 (2020), pp.1-6.
https://search.emarefa.net/detail/BIM-1186566
American Medical Association (AMA)
Rubin, David M.& Stacey, Neil T.& Matambo, Tonderayi& Vale, Claudia Do& Sussman, Martin J.& Snyman, Tracy…[et al.]. Toward Respiratory Support of Critically Ill COVID-19 Patients Using Repurposed Kidney Hollow Fiber Membrane Dialysers to Oxygenate the Blood. Journal of Healthcare Engineering. 2020. Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1186566
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1186566