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Antihepatitis B Surface Antigen and Hepatitis C Antibodies among Pregnant Women in an Urban Area of Mwanza City, Tanzania
Joint Authors
Mshana, Stephen E.
Mirambo, Mariam M.
Minja, Caroline A.
Silago, Vitus
Mujuni, Fridolin
Chibwe, Elieza
Kajoro, Edwin
Juma, Muhsin
Mkumbo, Emmanuel
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-06-18
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Background.
Hepatitis B and hepatitis C viruses (HBV and HCV) are life-threatening infections of public health importance due to their association with cirrhosis and hepatocellular carcinoma.
Despite HBV being moderately endemic in many low-income countries, there is no routine HBV vaccination among child bearing aged women making them at risk of transmitting infections to the foetus during pregnancy.
This study investigated the seroprevalence of antihepatitis B surface antibodies (anti-HBs) and HCV antibodies among pregnant women in Mwanza city to provide data that can be used in devising preventive strategies.
Methods.
A cross-sectional hospital-based study involving 339 pregnant women was conducted between June and July 2017.
Data were collected using structured data collection tool.
Detection of anti-HBs was performed using enzyme immunoassay while qualitative rapid immunochromatographic tests were employed to detect HCV antibodies.
Data was analyzed by using STATA version 13.
Results.
The mean age of the study participants was 25.6±5.8 years.
The prevalence of anti-HBs was 85/339 (25.1%, 95% CI: 20.4-29.6) while that of HCV antibodies was 1/333 (0.3%, 95% CI: 0.1-0.4).
By univariate logistic regression analysis, increase in age (OR: 1.04, 95% CI: 1.00-1.09, P=0.03), unknown HIV status (OR: 0.3, 95% CI: 0.11-0.79, P=0.035), and multigravidity (OR: 2.12, 95% CI: 1.18-3.8, P=0.038) were significantly associated with anti-HBs seropositivity.
Conclusion.
A significant proportion of pregnant women have anti-HBs while the seroprevalence of HCV is low among pregnant women in the city of Mwanza.
Routine screening of HBV among pregnant women coupled with appropriate management should be emphasized in developing countries.
Further studies to determine seroprevalence of HCV are recommended across the country.
American Psychological Association (APA)
Chibwe, Elieza& Silago, Vitus& Kajoro, Edwin& Juma, Muhsin& Mkumbo, Emmanuel& Minja, Caroline A.…[et al.]. 2019. Antihepatitis B Surface Antigen and Hepatitis C Antibodies among Pregnant Women in an Urban Area of Mwanza City, Tanzania. Journal of Pregnancy،Vol. 2019, no. 2019, pp.1-5.
https://search.emarefa.net/detail/BIM-1186670
Modern Language Association (MLA)
Chibwe, Elieza…[et al.]. Antihepatitis B Surface Antigen and Hepatitis C Antibodies among Pregnant Women in an Urban Area of Mwanza City, Tanzania. Journal of Pregnancy No. 2019 (2019), pp.1-5.
https://search.emarefa.net/detail/BIM-1186670
American Medical Association (AMA)
Chibwe, Elieza& Silago, Vitus& Kajoro, Edwin& Juma, Muhsin& Mkumbo, Emmanuel& Minja, Caroline A.…[et al.]. Antihepatitis B Surface Antigen and Hepatitis C Antibodies among Pregnant Women in an Urban Area of Mwanza City, Tanzania. Journal of Pregnancy. 2019. Vol. 2019, no. 2019, pp.1-5.
https://search.emarefa.net/detail/BIM-1186670
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1186670