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Biomarkers of Oxidative Stress as Indicators of Fungi Environmental Pollution in Balbc Albino Mice Monitored from South West, Nigeria
Joint Authors
Odebode, Adeyinka
Adekunle, Adedotun
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-04-07
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
The presence and detection of common airborne fungi in an area are important for the prevention and treatment of allergic fungal diseases.
Because of the ubiquitous nature of fungi, the effect of four different fungal species in production of antioxidant and reactive oxygen species production in balb/c albino mice was investigated.
Fifty-four balb/c mice were randomly divided into eight groups (n = 6) and a normal control group.
Four different fungal plates, comprising Aspergillus flavus, Aspergillus penicillioides, Penicillium citrinum, and Penicillium chrysogenum, which were the most abundant fungi species sampled in the environment were cultured for one week to make 2.3 x 107 and 3.2 x 105 spores and injected intranasally in sterile saline into the nostrils of each of the mice.
Results showed that all fungal inoculated organism produced statistically (P<0.05) significant reactive oxygen species while antioxidant parameters were significantly decreased in a dose dependent manner compared with normal control mice.
It is therefore concluded that Aspergillus flavus, Aspergillus penicillioides, Penicillium citrinum, and Penicillium chrysogenum can alter and decrease immune function in balb/c mice.
Therefore, this study was conducted to identify the most common airborne fungal species present in Southwest Nigeria and to study their allergic reactions.
American Psychological Association (APA)
Odebode, Adeyinka& Adekunle, Adedotun. 2019. Biomarkers of Oxidative Stress as Indicators of Fungi Environmental Pollution in Balbc Albino Mice Monitored from South West, Nigeria. Journal of Pathogens،Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1186729
Modern Language Association (MLA)
Odebode, Adeyinka& Adekunle, Adedotun. Biomarkers of Oxidative Stress as Indicators of Fungi Environmental Pollution in Balbc Albino Mice Monitored from South West, Nigeria. Journal of Pathogens No. 2019 (2019), pp.1-9.
https://search.emarefa.net/detail/BIM-1186729
American Medical Association (AMA)
Odebode, Adeyinka& Adekunle, Adedotun. Biomarkers of Oxidative Stress as Indicators of Fungi Environmental Pollution in Balbc Albino Mice Monitored from South West, Nigeria. Journal of Pathogens. 2019. Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1186729
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1186729