Chlamydia and Its Many Ways of Escaping the Host Immune System
Joint Authors
Chambers, James
Wong, Won Fen
Gupta, Rishein
Arulanandam, Bernard
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-08-06
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
The increasing number of new cases of Chlamydia infection worldwide may be attributed to the pathogen’s ability to evade various host immune responses.
Summarized here are means of evasion utilized by Chlamydia enabling survival in a hostile host environment.
The pathogen's persistence involves a myriad of molecular interactions manifested in a variety of ways, e.g., formation of membranous intracytoplasmic inclusions and cytokine-induced amino acid synthesis, paralysis of phagocytic neutrophils, evasion of phagocytosis, inhibition of host cell apoptosis, suppression of antigen presentation, and induced expression of a check point inhibitor of programmed host cell death.
Future studies could focus on the targeting of these molecules associated with immune evasion, thus limiting the spread and tissue damage caused by this pathogen.
American Psychological Association (APA)
Wong, Won Fen& Chambers, James& Gupta, Rishein& Arulanandam, Bernard. 2019. Chlamydia and Its Many Ways of Escaping the Host Immune System. Journal of Pathogens،Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1186733
Modern Language Association (MLA)
Wong, Won Fen…[et al.]. Chlamydia and Its Many Ways of Escaping the Host Immune System. Journal of Pathogens No. 2019 (2019), pp.1-9.
https://search.emarefa.net/detail/BIM-1186733
American Medical Association (AMA)
Wong, Won Fen& Chambers, James& Gupta, Rishein& Arulanandam, Bernard. Chlamydia and Its Many Ways of Escaping the Host Immune System. Journal of Pathogens. 2019. Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1186733
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1186733