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A Novel Interpretation for Arterial Pulse Pressure Amplification in Health and Disease
Joint Authors
Armentano, Ricardo L.
Alfonso, Manuel R.
Cymberknop, Leandro J.
Ghigo, Arthur R.
Pessana, Franco M.
Legnani, Walter E.
Source
Journal of Healthcare Engineering
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-01-16
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Arterial pressure waves have been described in one dimension using several approaches, such as lumped (Windkessel) or distributed (using Navier-Stokes equations) models.
An alternative approach consists of modeling blood pressure waves using a Korteweg-de Vries (KdV) equation and representing pressure waves as combinations of solitons.
This model captures many key features of wave propagation in the systemic network and, in particular, pulse pressure amplification (PPA), which is a mechanical biomarker of cardiovascular risk.
The main objective of this work is to compare the propagation dynamics described by a KdV equation in a human-like arterial tree using acquired pressure waves.
Furthermore, we analyzed the ability of our model to reproduce induced elastic changes in PPA due to different pathological conditions.
To this end, numerical simulations were performed using acquired central pressure signals from different subject groups (young, adults, and hypertensive) as input and then comparing the output of the model with measured radial artery pressure waveforms.
Pathological conditions were modeled as changes in arterial elasticity (E).
Numerical results showed that the model was able to propagate acquired pressure waveforms and to reproduce PPA variations as a consequence of elastic changes.
Calculated elasticity for each group was in accordance with the existing literature.
American Psychological Association (APA)
Alfonso, Manuel R.& Armentano, Ricardo L.& Cymberknop, Leandro J.& Ghigo, Arthur R.& Pessana, Franco M.& Legnani, Walter E.. 2018. A Novel Interpretation for Arterial Pulse Pressure Amplification in Health and Disease. Journal of Healthcare Engineering،Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1186902
Modern Language Association (MLA)
Alfonso, Manuel R.…[et al.]. A Novel Interpretation for Arterial Pulse Pressure Amplification in Health and Disease. Journal of Healthcare Engineering No. 2018 (2018), pp.1-9.
https://search.emarefa.net/detail/BIM-1186902
American Medical Association (AMA)
Alfonso, Manuel R.& Armentano, Ricardo L.& Cymberknop, Leandro J.& Ghigo, Arthur R.& Pessana, Franco M.& Legnani, Walter E.. A Novel Interpretation for Arterial Pulse Pressure Amplification in Health and Disease. Journal of Healthcare Engineering. 2018. Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1186902
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1186902