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Predicting Interactions between Virus and Host Proteins Using Repeat Patterns and Composition of Amino Acids
Joint Authors
Han, Kyungsook
Huang, De-Shuang
Alguwaizani, Saud
Park, Byungkyu
Zhou, Xiang
Source
Journal of Healthcare Engineering
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-05-09
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Previous methods for predicting protein-protein interactions (PPIs) were mainly focused on PPIs within a single species, but PPIs across different species have recently emerged as an important issue in some areas such as viral infection.
The primary focus of this study is to predict PPIs between virus and its targeted host, which are involved in viral infection.
We developed a general method that predicts interactions between virus and host proteins using the repeat patterns and composition of amino acids.
In independent testing of the method with PPIs of new viruses and hosts, it showed a high performance comparable to the best performance of other methods for single virus-host PPIs.
In comparison of our method with others using same datasets, our method outperformed the others.
The repeat patterns and composition of amino acids are simple, yet powerful features for predicting virus-host PPIs.
The method developed in this study will help in finding new virus-host PPIs for which little information is available.
American Psychological Association (APA)
Alguwaizani, Saud& Park, Byungkyu& Zhou, Xiang& Huang, De-Shuang& Han, Kyungsook. 2018. Predicting Interactions between Virus and Host Proteins Using Repeat Patterns and Composition of Amino Acids. Journal of Healthcare Engineering،Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1186908
Modern Language Association (MLA)
Alguwaizani, Saud…[et al.]. Predicting Interactions between Virus and Host Proteins Using Repeat Patterns and Composition of Amino Acids. Journal of Healthcare Engineering No. 2018 (2018), pp.1-9.
https://search.emarefa.net/detail/BIM-1186908
American Medical Association (AMA)
Alguwaizani, Saud& Park, Byungkyu& Zhou, Xiang& Huang, De-Shuang& Han, Kyungsook. Predicting Interactions between Virus and Host Proteins Using Repeat Patterns and Composition of Amino Acids. Journal of Healthcare Engineering. 2018. Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1186908
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1186908