Involvement of lncRNAs and Macrophages: Potential Regulatory Link to Angiogenesis
Joint Authors
Source
Journal of Immunology Research
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-02-29
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Macrophages are involved in angiogenesis, an essential process for organ growth and tissue repair, and could contribute to the pathogenesis of angiogenesis-related diseases such as malignant tumors and diabetic retinopathy.
Recently, long noncoding RNAs (lncRNAs) have been proved to be important in cell differentiation, organismal development, and various diseases of pathological angiogenesis.
Moreover, it has been indicated that numerous lncRNAs exhibit different functions in macrophage infiltration and polarization and regulate the secretion of inflammatory cytokines released by macrophages.
Therefore, the focus of macrophage-related lncRNAs could be considered to be a potential method in therapeutic targeting angiogenesis-related diseases.
This review mainly summarizes the roles played by lncRNAs which associated with macrophages in angiogenesis.
The possible mechanisms of the regulatory link between lncRNAs and macrophages in various angiogenesis-related diseases were also discussed.
American Psychological Association (APA)
Jia, Yang& Zhou, Yedi. 2020. Involvement of lncRNAs and Macrophages: Potential Regulatory Link to Angiogenesis. Journal of Immunology Research،Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1186918
Modern Language Association (MLA)
Jia, Yang& Zhou, Yedi. Involvement of lncRNAs and Macrophages: Potential Regulatory Link to Angiogenesis. Journal of Immunology Research No. 2020 (2020), pp.1-9.
https://search.emarefa.net/detail/BIM-1186918
American Medical Association (AMA)
Jia, Yang& Zhou, Yedi. Involvement of lncRNAs and Macrophages: Potential Regulatory Link to Angiogenesis. Journal of Immunology Research. 2020. Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1186918
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1186918