Galectin-3 Is a Potential Mediator for Atherosclerosis
Joint Authors
Li, Hong
Gao, Ziyu
Liu, Zhongni
Wang, Rui
Zheng, Yinghong
Yang, Liming
Source
Journal of Immunology Research
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-02-14
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Atherosclerosis is a multifactorial chronic inflammatory arterial disease forming the pathological basis of many cardiovascular diseases such as coronary heart disease, heart failure, and stroke.
Numerous studies have implicated inflammation as a key player in the initiation and progression of atherosclerosis.
Galectin-3 (Gal-3) is a 30 kDa β-galactose, highly conserved and widely distributed intracellularly and extracellularly.
Gal-3 has been demonstrated in recent years to be a novel inflammatory factor participating in the process of intravascular inflammation, lipid endocytosis, macrophage activation, cellular proliferation, monocyte chemotaxis, and cell adhesion.
This review focuses on the role of Gal-3 in atherosclerosis and the mechanism involved and several classical Gal-3 agonists and antagonists in the current studies.
American Psychological Association (APA)
Gao, Ziyu& Liu, Zhongni& Wang, Rui& Zheng, Yinghong& Li, Hong& Yang, Liming. 2020. Galectin-3 Is a Potential Mediator for Atherosclerosis. Journal of Immunology Research،Vol. 2020, no. 2020, pp.1-11.
https://search.emarefa.net/detail/BIM-1187295
Modern Language Association (MLA)
Gao, Ziyu…[et al.]. Galectin-3 Is a Potential Mediator for Atherosclerosis. Journal of Immunology Research No. 2020 (2020), pp.1-11.
https://search.emarefa.net/detail/BIM-1187295
American Medical Association (AMA)
Gao, Ziyu& Liu, Zhongni& Wang, Rui& Zheng, Yinghong& Li, Hong& Yang, Liming. Galectin-3 Is a Potential Mediator for Atherosclerosis. Journal of Immunology Research. 2020. Vol. 2020, no. 2020, pp.1-11.
https://search.emarefa.net/detail/BIM-1187295
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1187295