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Platelet-Rich Plasma, Hydroxyapatite, and Chitosan in the Bone and Cartilaginous Regeneration of Femoral Trochlea in Rabbits: Clinical, Radiographic, and Histomorphometric Evaluations
Joint Authors
Segundo, Francisco Alipio de Sousa
Costa, Edla Iris de Sousa
Azevedo, Adílio Santos de
Araújo, Ana Lucélia de
Silva, Ana Clara de França
de Lima, Gabriel Goetten
de Sá, Marcelo Jorge Cavalcanti
Source
Journal of Healthcare Engineering
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-06-24
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
The aim of this study was to evaluate the trochlear bone and cartilaginous regeneration of rabbits using the association of PRP, chitosan, and hydroxyapatite.
Hole was made in rabbit troches, one hole in each animal remained empty (group C), and one was filled by a combination of PRP, chitosan, and hydroxyapatite (group T).
Clinical-orthopedic, radiographic, and histomorphometric evaluations were performed.
Clinical-orthopedic evaluation showed lameness of two members of the T group and one member of group C.
The radiographic evaluation showed that the T group showed absence of subchondral bone reaction (33%).
The presence of moderate subchondral bone reaction was more frequently reported in group C with 67%.
Microscopic evaluation revealed a presence of tissue neoformation, composed of connective tissue.
Microscopic findings were similar in both groups, with a difference in the amount of neoformed tissue being perceptible, which was confirmed after the morphometric analysis, which revealed a significant difference in the quantity of newly formed tissue at the bone/cartilage/implant interface.
The composite base of the association of chitosan, hydroxyapatite, and platelet-rich plasma favored bone and cartilage healing.
American Psychological Association (APA)
Segundo, Francisco Alipio de Sousa& Costa, Edla Iris de Sousa& Azevedo, Adílio Santos de& Araújo, Ana Lucélia de& Silva, Ana Clara de França& de Lima, Gabriel Goetten…[et al.]. 2018. Platelet-Rich Plasma, Hydroxyapatite, and Chitosan in the Bone and Cartilaginous Regeneration of Femoral Trochlea in Rabbits: Clinical, Radiographic, and Histomorphometric Evaluations. Journal of Healthcare Engineering،Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1187549
Modern Language Association (MLA)
Segundo, Francisco Alipio de Sousa…[et al.]. Platelet-Rich Plasma, Hydroxyapatite, and Chitosan in the Bone and Cartilaginous Regeneration of Femoral Trochlea in Rabbits: Clinical, Radiographic, and Histomorphometric Evaluations. Journal of Healthcare Engineering No. 2018 (2018), pp.1-6.
https://search.emarefa.net/detail/BIM-1187549
American Medical Association (AMA)
Segundo, Francisco Alipio de Sousa& Costa, Edla Iris de Sousa& Azevedo, Adílio Santos de& Araújo, Ana Lucélia de& Silva, Ana Clara de França& de Lima, Gabriel Goetten…[et al.]. Platelet-Rich Plasma, Hydroxyapatite, and Chitosan in the Bone and Cartilaginous Regeneration of Femoral Trochlea in Rabbits: Clinical, Radiographic, and Histomorphometric Evaluations. Journal of Healthcare Engineering. 2018. Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1187549
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1187549