Utility of Saline-Induced Resting Full-Cycle Ratio Compared with Resting Full-Cycle Ratio and Fractional Flow Reserve
Joint Authors
Sato, Takao
Goto, Sonoka
Ohta, Yusuke
Taya, Yuji
Yuasa, Sho
Takahashi, Minoru
Aizawa, Yoshifusa
Okabe, Masaaki
Source
Journal of Interventional Cardiology
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-04-07
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background.
The saline-induced distal coronary pressure/aortic pressure ratio predicted fractional flow reserve (FFR).
The resting full-cycle ratio (RFR) represents the maximal relative pressure difference in a cardiac cycle.
Therefore, the present study aimed to compare the results of saline-induced RFR (sRFR) with FFR.
Methods.
Seventy consecutive lesions with only moderate stenosis were included.
The FFR, RFR, and sRFR values were compared.
The sRFR was assessed using an intracoronary bolus infusion of saline (2 mL/s) for five heartbeats.
The FFR was obtained after an intravenous injection of papaverine.
Results.
Overall, the FFR, sRFR, and RFR values were 0.78 ± 0.12, 0.79 ± 0.13, and 0.83 ± 0.14, respectively.
With regard to anatomical morphology were 40, 18, and 12 cases of focal, diffuse, and tandem lesion.
There was a significant correlation between the sRFR and FFR (R = 0.96, p<0.01).
There were also significant correlations between the sRFR and FFR in the left coronary and right coronary artery (R = 0.95, p<0.01 and R = 0.98, p<0.01).
Furthermore, significant correlations between sRFR and FFR were observed in not only focal but also in nonfocal lesion including tandem and diffuse lesions (R = 0.93, p<0.01 and R = 0.97, p<0.01).
A close agreement on FFR and sRFR was shown using the Bland–Altman analysis (95% CI of agreement: −0.08–0.07).
In the receiver operating characteristic curve analysis, the cutoff value of sRFR to predict an FFR of 0.80 was 0.81 (area under curve, 0.97; sensitivity 90.6%; and specificity 98.2%).
Conclusion.
The sRFR can accurately and safely predict the FFR and might be effective for diagnosing ischemia.
American Psychological Association (APA)
Sato, Takao& Goto, Sonoka& Ohta, Yusuke& Taya, Yuji& Yuasa, Sho& Takahashi, Minoru…[et al.]. 2020. Utility of Saline-Induced Resting Full-Cycle Ratio Compared with Resting Full-Cycle Ratio and Fractional Flow Reserve. Journal of Interventional Cardiology،Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1187824
Modern Language Association (MLA)
Sato, Takao…[et al.]. Utility of Saline-Induced Resting Full-Cycle Ratio Compared with Resting Full-Cycle Ratio and Fractional Flow Reserve. Journal of Interventional Cardiology No. 2020 (2020), pp.1-7.
https://search.emarefa.net/detail/BIM-1187824
American Medical Association (AMA)
Sato, Takao& Goto, Sonoka& Ohta, Yusuke& Taya, Yuji& Yuasa, Sho& Takahashi, Minoru…[et al.]. Utility of Saline-Induced Resting Full-Cycle Ratio Compared with Resting Full-Cycle Ratio and Fractional Flow Reserve. Journal of Interventional Cardiology. 2020. Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1187824
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1187824