A Derivative Spectrometric Method for Hydroquinone Determination in the Presence of Kojic Acid, Glycolic Acid, and Ascorbic Acid
Joint Authors
Popa, Dana-Elena
Buleandra, Mihaela
Moldovan, Zenovia
David, Iulia Gabriela
Badea, Irinel Adriana
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-01-18
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
A new, simple, and sensitive spectrometric method was developed for hydroquinone (HQ) determination in the presence of other depigmenting agents (kojic acid (KA), glycolic acid (GA), and ascorbic acid (AA)), commonly introduced in skin lightening products.
The method is based on the oxidation of the depigmenting agents by potassium dichromate in sulfuric acid medium and subsequent measurement of the amplitude of the first-order derivative absorption spectrum at 268 nm.
By applying the zero-crossing method, at this wavelength, the oxidation products of KA, AA, and GA do not interfere in the indirect determination of HQ.
Beer’s law was obeyed in the range of 0.22–22 μg·mL−1 HQ, with a detection limit of 0.07 μg·mL−1.
The developed method was applied with good results for the first time to the rapid determination of HQ in binary, ternary, and quaternary mixtures, thus proving that it could represent an effective tool for various skin lightening products analyses.
American Psychological Association (APA)
Moldovan, Zenovia& Popa, Dana-Elena& David, Iulia Gabriela& Buleandra, Mihaela& Badea, Irinel Adriana. 2017. A Derivative Spectrometric Method for Hydroquinone Determination in the Presence of Kojic Acid, Glycolic Acid, and Ascorbic Acid. Journal of Spectroscopy،Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1187848
Modern Language Association (MLA)
Moldovan, Zenovia…[et al.]. A Derivative Spectrometric Method for Hydroquinone Determination in the Presence of Kojic Acid, Glycolic Acid, and Ascorbic Acid. Journal of Spectroscopy No. 2017 (2017), pp.1-9.
https://search.emarefa.net/detail/BIM-1187848
American Medical Association (AMA)
Moldovan, Zenovia& Popa, Dana-Elena& David, Iulia Gabriela& Buleandra, Mihaela& Badea, Irinel Adriana. A Derivative Spectrometric Method for Hydroquinone Determination in the Presence of Kojic Acid, Glycolic Acid, and Ascorbic Acid. Journal of Spectroscopy. 2017. Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1187848
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1187848