Incidence, Predictors, and Outcome of Paravalvular Leak after Transcatheter Aortic Valve Implantation
Joint Authors
Ou, Yuan-weixiang
Li, Yi-jian
Wei, Xin
Feng, Yuan
Chen, Mao
Hagar, Abdullah
Peng, Yong
Xu, Yuanning
Wang, Zijie
Wang, Xi
Shah, Jageshwar-Prasad
Sihag, Vivendar
Source
Journal of Interventional Cardiology
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-05-22
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Background.
Paravalvular leak (PVL) is common after transcatheter aortic valve implantation (TAVI) and has been linked with worse survival.
This study aimed to investigate the determinants and outcome of PVL after TAVI and determine the role of aortic valve calcification (AVC) distribution in predicting PVL.
Methods and Results.
This was a retrospective cohort study of 270 consecutive patients who underwent TAVI.
Determinants and outcomes of ≥mild PVL were assessed.
Matching rates of PVL jet with AVC distribution were calculated.
AVC volume, larger annulus dimensions, and transvalvular peak velocity were risk factors for ≥mild PVL after TAVI.
AVC volume was an independent predictor of ≥mild PVL.
On the other hand, annulus ellipticity, left ventricular outflow tract nontubularity, and diameter-derived prosthesis mismatch were not found to predict PVL after TAVI.
PVL jet matched, in varying proportions, with calcification at all aortic root regions, and the highest matching rate was with calcifications at body of leaflets.
Moreover, matching rates were less with commissure compared to cusp calcifications.
Mild or greater PVL was not associated with all-cause and cardiovascular mortality up to 1-year follow-up.
Conclusion.
≥mild PVL after TAVI is common and can be predicted by aortic root calcification volume, larger annulus dimensions, and pre-TAVI transvalvular peak velocity, with calcification volume being an independent predictor for PVL.
However, annulus ellipticity, left ventricular outflow tract nontubularity, and diameter-derived prosthesis mismatch had no role in predicting PVL.
Importantly, body of leaflet calcifications (versus annulus and tip of leaflet) and cusp calcifications (versus commissure calcification) are more important in predicting PVL.
No association between ≥mild PVL and increased risk of all-cause and cardiovascular mortality at 1-year follow-up.
American Psychological Association (APA)
Hagar, Abdullah& Li, Yi-jian& Wei, Xin& Peng, Yong& Xu, Yuanning& Ou, Yuan-weixiang…[et al.]. 2020. Incidence, Predictors, and Outcome of Paravalvular Leak after Transcatheter Aortic Valve Implantation. Journal of Interventional Cardiology،Vol. 2020, no. 2020, pp.1-11.
https://search.emarefa.net/detail/BIM-1187872
Modern Language Association (MLA)
Hagar, Abdullah…[et al.]. Incidence, Predictors, and Outcome of Paravalvular Leak after Transcatheter Aortic Valve Implantation. Journal of Interventional Cardiology No. 2020 (2020), pp.1-11.
https://search.emarefa.net/detail/BIM-1187872
American Medical Association (AMA)
Hagar, Abdullah& Li, Yi-jian& Wei, Xin& Peng, Yong& Xu, Yuanning& Ou, Yuan-weixiang…[et al.]. Incidence, Predictors, and Outcome of Paravalvular Leak after Transcatheter Aortic Valve Implantation. Journal of Interventional Cardiology. 2020. Vol. 2020, no. 2020, pp.1-11.
https://search.emarefa.net/detail/BIM-1187872
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1187872