Sirolimus-Eluting Balloon for the Treatment of Coronary Lesions in Complex ACS Patients: The SELFIE Registry
Joint Authors
Caiazzo, Gianluca
De Michele, Mario
Golino, Luca
Manganiello, Vincenzo
Fattore, Luciano
Source
Journal of Interventional Cardiology
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-10-17
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background.
Sirolimus-coated balloons (SCBs) represent a novel therapeutic option for both in-stent restenosis (ISR) and de novo coronary lesions treatment, especially in small vessels.
Our registry sought to evaluate the procedural and clinical outcomes of such devices in a complex acute coronary syndrome (ACS) clinical setting.
Methods and Results.
We treated 74 consecutive patients with percutaneous coronary intervention (PCI) with at least 1 SCB used for ISR and/or de novo coronary lesion in small vessels at our institution.
Sixty-two patients presented with ACS, and their data were included in our analysis.
The mean age was 67 ± 10 years, and patients presenting with ST-elevated myocardial infarction (STEMI) were 14 (23%).
De novo lesions were 52%, whereas ISR was 48%.
Procedural success occurred in 100% of the cases.
At the 11 ± 7 months follow-up, major adverse cardiovascular events (MACEs) were 3 (4.8%).
Cardiovascular death (CD) occurred in 1 (1.6%) patient and myocardial infarction (MI) in 2 patients (3.2%) as well as ischemia-driven target lesion revascularization (TLR).
One probable subacute thrombosis occurred (1.6%) with no major bleedings.
In a subgroup analysis, the incidence of MACE did not show significant differences between patients treated for de novo lesions and ISR (HR: 0.239; CI 95%: 0.003–16.761, p=0.509).
Conclusions.
In the SELFIE prospective registry, SCB showed a good safety and efficacy profile for the treatment of coronary lesions, both ISR and/or de novo in small vessels, in a complex ACS population of patients at the 11 ± 7 months follow-up.
American Psychological Association (APA)
Caiazzo, Gianluca& De Michele, Mario& Golino, Luca& Manganiello, Vincenzo& Fattore, Luciano. 2020. Sirolimus-Eluting Balloon for the Treatment of Coronary Lesions in Complex ACS Patients: The SELFIE Registry. Journal of Interventional Cardiology،Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1187889
Modern Language Association (MLA)
Caiazzo, Gianluca…[et al.]. Sirolimus-Eluting Balloon for the Treatment of Coronary Lesions in Complex ACS Patients: The SELFIE Registry. Journal of Interventional Cardiology No. 2020 (2020), pp.1-7.
https://search.emarefa.net/detail/BIM-1187889
American Medical Association (AMA)
Caiazzo, Gianluca& De Michele, Mario& Golino, Luca& Manganiello, Vincenzo& Fattore, Luciano. Sirolimus-Eluting Balloon for the Treatment of Coronary Lesions in Complex ACS Patients: The SELFIE Registry. Journal of Interventional Cardiology. 2020. Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1187889
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1187889