Angio-Based Index of Microcirculatory Resistance for the Assessment of the Coronary Resistance: A Proof of Concept Study
Joint Authors
Campo, Gianluca
Tebaldi, Matteo
Biscaglia, Simone
Di Girolamo, Domenico
Erriquez, Andrea
Penzo, Carlo
Tumscitz, Carlo
Source
Journal of Interventional Cardiology
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-10-26
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Background.
The study of coronary microcirculation has gained increasing consideration and importance in cath lab.
Despite the increase of evidence, its use still remains very limited.
QFR is a novel angio-based approach for the evaluation of coronary stenosis.
The aim of our study was to use the QFR assessment in stable patients to recreate the IMR formula and to correlate the result of the two techniques.
Methods.
From June 1, 2019, to February 29, 2019, 200 patients with CCS and indication of coronary artery angiography and referred to the cath lab of the University Hospital of Ferrara (Italy) were enrolled.
After baseline coronary angiogram, quantitative flow ratio, fractional flow reserve, and index of microcirculatory resistance evaluation were performed.
Results.
Pearson correlation (r) between angio-based index of microcirculatory resistance (A-IMR) and IMR 0.32 with R2 = 0.098, P=0.03: McNemar test showed a difference between the two tests of 6.82% with 95% CI from –12.05% to 22.89%, which is not significant (P=0.60).
Bland and Altman plot showed a mean difference of 23.3 (from −26.5 to 73.1).
Sensitivity, specificity, NPV, and PPV were 70%, 83.3%, 75%, and 70% for A-IMR value >44.2.
The area under the ROC curve for A-IMR was 0.76 (95% CI 0.61–0.88, P=0.0003).
Conclusion.
We have validated for the first time the formula of the A-IMR, a tool for the calculation of microvascular resistance which does not require the use of pressure guides and the induction of hyperemia.
American Psychological Association (APA)
Tebaldi, Matteo& Biscaglia, Simone& Di Girolamo, Domenico& Erriquez, Andrea& Penzo, Carlo& Tumscitz, Carlo…[et al.]. 2020. Angio-Based Index of Microcirculatory Resistance for the Assessment of the Coronary Resistance: A Proof of Concept Study. Journal of Interventional Cardiology،Vol. 2020, no. 2020, pp.1-4.
https://search.emarefa.net/detail/BIM-1187891
Modern Language Association (MLA)
Tebaldi, Matteo…[et al.]. Angio-Based Index of Microcirculatory Resistance for the Assessment of the Coronary Resistance: A Proof of Concept Study. Journal of Interventional Cardiology No. 2020 (2020), pp.1-4.
https://search.emarefa.net/detail/BIM-1187891
American Medical Association (AMA)
Tebaldi, Matteo& Biscaglia, Simone& Di Girolamo, Domenico& Erriquez, Andrea& Penzo, Carlo& Tumscitz, Carlo…[et al.]. Angio-Based Index of Microcirculatory Resistance for the Assessment of the Coronary Resistance: A Proof of Concept Study. Journal of Interventional Cardiology. 2020. Vol. 2020, no. 2020, pp.1-4.
https://search.emarefa.net/detail/BIM-1187891
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1187891