Mediators of Inflammation and Angiogenesis in Chronic Spontaneous Urticaria: Are They Potential Biomarkers of the Disease?

Joint Authors

Puxeddu, Ilaria
Pratesi, Federico
Migliorini, Paola
Ribatti, Domenico

Source

Mediators of Inflammation

Issue

Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-6, 6 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2017-09-05

Country of Publication

Egypt

No. of Pages

6

Main Subjects

Diseases

Abstract EN

In chronic spontaneous urticaria (CSU), different pathophysiological mechanisms, potentially responsible for the development of the disease, have been recently described.

It is likely that the activation of skin mast cells with consequent release of histamine and other proinflammatory mediators is responsible for vasodilation in the lesional skin of CSU.

However, the underlying causes of mast cell activation in the disease are largely unknown and remain to be identified.

Thus, in this review, we discuss new insights in the pathogenesis of CSU, focusing on inflammation and angiogenesis.

The understanding of these mechanisms will enable the identification of biomarkers useful for the diagnosis, follow-up, and management of CSU and will allow the development of novel, more specific, and patient-tailored therapies.

American Psychological Association (APA)

Puxeddu, Ilaria& Pratesi, Federico& Ribatti, Domenico& Migliorini, Paola. 2017. Mediators of Inflammation and Angiogenesis in Chronic Spontaneous Urticaria: Are They Potential Biomarkers of the Disease?. Mediators of Inflammation،Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1188316

Modern Language Association (MLA)

Puxeddu, Ilaria…[et al.]. Mediators of Inflammation and Angiogenesis in Chronic Spontaneous Urticaria: Are They Potential Biomarkers of the Disease?. Mediators of Inflammation No. 2017 (2017), pp.1-6.
https://search.emarefa.net/detail/BIM-1188316

American Medical Association (AMA)

Puxeddu, Ilaria& Pratesi, Federico& Ribatti, Domenico& Migliorini, Paola. Mediators of Inflammation and Angiogenesis in Chronic Spontaneous Urticaria: Are They Potential Biomarkers of the Disease?. Mediators of Inflammation. 2017. Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1188316

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1188316