Liver Regeneration: Analysis of the Main Relevant Signaling Molecules
Joint Authors
Chen, En-Qiang
Tang, Hong
Tao, Yachao
Wang, Menglan
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-08-30
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Liver regeneration is a highly organized tissue regrowth process and is the most important reaction of the liver to injury.
The overall process of liver regeneration includes three phases: priming stage, proliferative phase, and termination phase.
The initial step aims to induce hepatocytes to be sensitive to growth factors with the aid of some cytokines, including TNF-α and IL-6.
The proliferation phase promotes hepatocytes to re-enter G1 with the stimulation of growth factors.
While during the termination stage, hepatocytes will discontinue to proliferate to maintain normal liver mass and function.
Except for cytokine- and growth factor-mediated pathways involved in regulating liver regeneration, new substances and technologies emerge to influence the regenerative process.
Here, we reviewed novel and important signaling molecules involved in the process of liver regeneration to provide a cue for further research.
American Psychological Association (APA)
Tao, Yachao& Wang, Menglan& Chen, En-Qiang& Tang, Hong. 2017. Liver Regeneration: Analysis of the Main Relevant Signaling Molecules. Mediators of Inflammation،Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1188320
Modern Language Association (MLA)
Tao, Yachao…[et al.]. Liver Regeneration: Analysis of the Main Relevant Signaling Molecules. Mediators of Inflammation No. 2017 (2017), pp.1-9.
https://search.emarefa.net/detail/BIM-1188320
American Medical Association (AMA)
Tao, Yachao& Wang, Menglan& Chen, En-Qiang& Tang, Hong. Liver Regeneration: Analysis of the Main Relevant Signaling Molecules. Mediators of Inflammation. 2017. Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1188320
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1188320