In Vitro Toxic Effect of Biomaterials Coated with Silver Tungstate or Silver Molybdate Microcrystals
Joint Authors
Vergani, C. E.
Siqueira, Walter Luiz
Pellissari, Claudia Viviane Guimarães
Pavarina, Ana Claudia
Sanitá, Paula Volpato
Jorge, Janaina Habib
Longo, E.
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-01-28
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Purpose.
This study evaluated the cytotoxicity of antimicrobial silver tungstate (Ag2WO4) or silver molybdate (Ag2MoO4) microcrystals coating biomaterials.
Materials and Methods.
The coating procedure was performed onto titanium, zirconia, and acrylic resin specimens.
Eluates of the coated specimens were obtained, which were used for cytotoxicity analyses, including Alamar Blue, MTT, and CytoTox-ONE tests.
Data were analyzed using two-way ANOVA, followed by the Tukey test (α = 0.05).
The results of each experimental group were also compared to those of the control of living cells, taken as 100% cell viability.
Results.
In general, it was observed that the percentage of living cells from all biomaterials coated with both microcrystals was statistically different compared to the ones from the uncoated sample groups, except for the results from MTT of specimens of Ti coated with α-Ag2MoO4.
All uncoated biomaterials were classified as noncytotoxic by the three assays used in the present study.
It was observed that the microcrystals in solution were strongly cytotoxic, with death of almost 100% of cells, from the analysis of the results of the Alamar Blue assay.
Conclusion.
The most biomaterials coated with both microcrystals showed some degree of cytotoxicity in the different assays.
The results described herein should be seen as an alert to the use of microcrystals, which can expose patients to health risks.
American Psychological Association (APA)
Pellissari, Claudia Viviane Guimarães& Vergani, C. E.& Longo, E.& Pavarina, Ana Claudia& Sanitá, Paula Volpato& Siqueira, Walter Luiz…[et al.]. 2020. In Vitro Toxic Effect of Biomaterials Coated with Silver Tungstate or Silver Molybdate Microcrystals. Journal of Nanomaterials،Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1188387
Modern Language Association (MLA)
Pellissari, Claudia Viviane Guimarães…[et al.]. In Vitro Toxic Effect of Biomaterials Coated with Silver Tungstate or Silver Molybdate Microcrystals. Journal of Nanomaterials No. 2020 (2020), pp.1-9.
https://search.emarefa.net/detail/BIM-1188387
American Medical Association (AMA)
Pellissari, Claudia Viviane Guimarães& Vergani, C. E.& Longo, E.& Pavarina, Ana Claudia& Sanitá, Paula Volpato& Siqueira, Walter Luiz…[et al.]. In Vitro Toxic Effect of Biomaterials Coated with Silver Tungstate or Silver Molybdate Microcrystals. Journal of Nanomaterials. 2020. Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1188387
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1188387