Roles of Cells from the Arterial Vessel Wall in Atherosclerosis
Joint Authors
Wang, Zhiyan
Wang, Yi
Wang, Di
Zhang, Lili
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-06-07
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Atherosclerosis has been identified as a chronic inflammatory disease of the arterial vessel wall.
Accumulating evidence indicates that different cells from the tunica intima, media, adventitia, and perivascular adipose tissue not only comprise the intact and normal arterial vessel wall but also participate all in the inflammatory response of atherosclerosis via multiple intricate pathways.
For instance, endothelial dysfunction has historically been considered to be the initiator of the development of atherosclerosis.
The migration and proliferation of smooth muscle cells also play a pivotal role in the progression of atherosclerosis.
Additionally, the fibroblasts from the adventitia and adipocytes from perivascular adipose tissue have received considerable attention given their special functions that contribute to atherosclerosis.
In addition, numerous types of cytokines produced by different cells from the arterial vessel wall, including endothelium-derived relaxing factors, endothelium-derived contracting factors, tumor necrosis factors, interleukin, adhesion molecules, interferon, and adventitium-derived relaxing factors, have been implicated in atherosclerosis.
Herein, we summarize the possible roles of different cells from the entire arterial vessel wall in the pathogenesis of atherosclerosis.
American Psychological Association (APA)
Wang, Di& Wang, Zhiyan& Zhang, Lili& Wang, Yi. 2017. Roles of Cells from the Arterial Vessel Wall in Atherosclerosis. Mediators of Inflammation،Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1188739
Modern Language Association (MLA)
Wang, Di…[et al.]. Roles of Cells from the Arterial Vessel Wall in Atherosclerosis. Mediators of Inflammation No. 2017 (2017), pp.1-9.
https://search.emarefa.net/detail/BIM-1188739
American Medical Association (AMA)
Wang, Di& Wang, Zhiyan& Zhang, Lili& Wang, Yi. Roles of Cells from the Arterial Vessel Wall in Atherosclerosis. Mediators of Inflammation. 2017. Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1188739
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1188739