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Effector and Regulatory T Cell Trafficking in Corneal Allograft Rejection
Joint Authors
Amouzegar, Afsaneh
Chauhan, Sunil K.
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-04-30
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Corneal transplantation is among the most prevalent and successful forms of solid tissue transplantation in humans.
Failure of corneal allograft is mainly due to immune-mediated destruction of the graft, a complex and highly coordinated process that involves elaborate interactions between cells of innate and adaptive immunity.
The migration of immune cells to regional lymphoid tissues and to the site of graft plays a central role in the immunopathogenesis of graft rejection.
Intricate interactions between adhesion molecules and their counter receptors on immune cells in conjunction with tissue-specific chemokines guide the trafficking of these cells to the draining lymph nodes and ultimately to the site of graft.
In this review, we discuss the cascade of chemokines and adhesion molecules that mediate the trafficking of effector and regulatory T cells during corneal allograft rejection.
American Psychological Association (APA)
Amouzegar, Afsaneh& Chauhan, Sunil K.. 2017. Effector and Regulatory T Cell Trafficking in Corneal Allograft Rejection. Mediators of Inflammation،Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1188790
Modern Language Association (MLA)
Amouzegar, Afsaneh& Chauhan, Sunil K.. Effector and Regulatory T Cell Trafficking in Corneal Allograft Rejection. Mediators of Inflammation No. 2017 (2017), pp.1-6.
https://search.emarefa.net/detail/BIM-1188790
American Medical Association (AMA)
Amouzegar, Afsaneh& Chauhan, Sunil K.. Effector and Regulatory T Cell Trafficking in Corneal Allograft Rejection. Mediators of Inflammation. 2017. Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1188790
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1188790