High Neutrophil-to-Lymphocyte Ratio Predicts Cardiovascular Mortality in Chronic Hemodialysis Patients
Joint Authors
Li, Han
Lu, Xiangxue
Xiong, Ruifang
Wang, Shixiang
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-02-21
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
The neutrophil-to-lymphocyte ratio (NLR) is a novel simple biomarker of inflammation.
It has emerged as a predictor of poor prognosis in cancer and cardiovascular disease in general population.
But little was known of its prognostic value in chronic hemodialysis (HD) patients.
Here we investigated the association between NLR and cardiovascular risk markers, including increased pulse pressure (PP), left ventricular mass index (LVMI) and intima-media thickness (IMT), and mortality in HD patients.
Two hundred and sixty-eight HD patients were enrolled in this study and were followed for 36 months.
The primary end point was all-cause mortality and cardiovascular mortality.
Multivariable Cox regression was used to calculate the adjusted hazard ratios for NLR on all-cause and cardiovascular survival.
We pinpointed that higher NLR in HD patients was a predictor of increased PP, LVMI, and IMT; HD patients with higher NLR had a lower survival at the end of the study; furthermore, high NLR was an independent predictor of all-cause and cardiovascular mortality when adjusted for other risk factors.
In conclusion, higher NLR in HD patients was associated with cardiovascular risk factors and mortality.
American Psychological Association (APA)
Li, Han& Lu, Xiangxue& Xiong, Ruifang& Wang, Shixiang. 2017. High Neutrophil-to-Lymphocyte Ratio Predicts Cardiovascular Mortality in Chronic Hemodialysis Patients. Mediators of Inflammation،Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1188816
Modern Language Association (MLA)
Li, Han…[et al.]. High Neutrophil-to-Lymphocyte Ratio Predicts Cardiovascular Mortality in Chronic Hemodialysis Patients. Mediators of Inflammation No. 2017 (2017), pp.1-8.
https://search.emarefa.net/detail/BIM-1188816
American Medical Association (AMA)
Li, Han& Lu, Xiangxue& Xiong, Ruifang& Wang, Shixiang. High Neutrophil-to-Lymphocyte Ratio Predicts Cardiovascular Mortality in Chronic Hemodialysis Patients. Mediators of Inflammation. 2017. Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1188816
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1188816