Effect of Lymphadenectomy on Survival in Early-Stage Type II Endometrial Carcinoma and Carcinosarcoma
Joint Authors
Vatansever, Dogan
Giray, Burak
Sozen, Hamdullah
Sahin Ersoy, Gulcin
Topuz, Samet
Iyibozkurt, A. Cem
Salihoglu, Yavuz
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-04-10
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Purpose.
We aimed to investigate whether systematic pelvic and paraaortic lymph node dissection delivers any survival advantage in a subgroup of patients with type II endometrial carcinoma and carcinosarcoma.
Methods.
We evaluated 135 patients with clinically early-stage (Stage I-II) type II endometrial carcinoma and carcinosarcoma who underwent systematic pelvic and paraaortic lymph node dissection or who did not undergo any lymph node dissection.
Results.
Overall survival (OS) and recurrence-free survivals (RFS) were significantly longer in the systematic lymph node dissection group (hazard ratio 0.28, 95% CI 0.13–0.62 p=0.002 for OS and hazard ratio 0.31, 95% CI 0.14–0.69 p=0.004 for RFS).
Multivariate analysis showed that lymph node dissection, age, lymph node metastasis, and adjuvant therapy were independent prognostic variables of OS and RFS.
Conclusions.
Systematic pelvic and paraaortic lymph node dissection independently and significantly prolongs the survival of patients with early-stage type II endometrial carcinoma and carcinosarcoma.
American Psychological Association (APA)
Vatansever, Dogan& Sozen, Hamdullah& Sahin Ersoy, Gulcin& Giray, Burak& Topuz, Samet& Iyibozkurt, A. Cem…[et al.]. 2020. Effect of Lymphadenectomy on Survival in Early-Stage Type II Endometrial Carcinoma and Carcinosarcoma. Journal of Oncology،Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1188840
Modern Language Association (MLA)
Vatansever, Dogan…[et al.]. Effect of Lymphadenectomy on Survival in Early-Stage Type II Endometrial Carcinoma and Carcinosarcoma. Journal of Oncology No. 2020 (2020), pp.1-6.
https://search.emarefa.net/detail/BIM-1188840
American Medical Association (AMA)
Vatansever, Dogan& Sozen, Hamdullah& Sahin Ersoy, Gulcin& Giray, Burak& Topuz, Samet& Iyibozkurt, A. Cem…[et al.]. Effect of Lymphadenectomy on Survival in Early-Stage Type II Endometrial Carcinoma and Carcinosarcoma. Journal of Oncology. 2020. Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1188840
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1188840