FAM64A Promotes Osteosarcoma Cell Growth and Metastasis and Is Mediated by miR-493
Joint Authors
Yan, Jun
Jiang, Ying
Yin, Zhiqi
Zhou, Chunlei
Gao, Qiang
Wang, Jingwen
Mu, Hong
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-02-24
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Aberrant expression of FAM64A was correlated with cell proliferation in various cancer types.
We examined the expression of FAM64A and the upstream gene miR-493 in OS.
The functions of miR-493 were revealed through extensive experiments.
We found an increase of FAM64A gene and protein in OS tissues.
Overexpression of FAM64A resulted in promoting tumor proliferation, migration, and invasion.
The miR-493 targeted and negatively regulated FAM64A.
Our data showed that upregulation of FAM64A in OS correlated with poor prognosis.
American Psychological Association (APA)
Jiang, Ying& Zhou, Chunlei& Gao, Qiang& Yin, Zhiqi& Wang, Jingwen& Mu, Hong…[et al.]. 2020. FAM64A Promotes Osteosarcoma Cell Growth and Metastasis and Is Mediated by miR-493. Journal of Oncology،Vol. 2020, no. 2020, pp.1-13.
https://search.emarefa.net/detail/BIM-1188875
Modern Language Association (MLA)
Jiang, Ying…[et al.]. FAM64A Promotes Osteosarcoma Cell Growth and Metastasis and Is Mediated by miR-493. Journal of Oncology No. 2020 (2020), pp.1-13.
https://search.emarefa.net/detail/BIM-1188875
American Medical Association (AMA)
Jiang, Ying& Zhou, Chunlei& Gao, Qiang& Yin, Zhiqi& Wang, Jingwen& Mu, Hong…[et al.]. FAM64A Promotes Osteosarcoma Cell Growth and Metastasis and Is Mediated by miR-493. Journal of Oncology. 2020. Vol. 2020, no. 2020, pp.1-13.
https://search.emarefa.net/detail/BIM-1188875
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1188875
