Research Progress on SlitRobo Pathway in Pancreatic Cancer: Emerging and Promising
Joint Authors
Ding, Cheng
Li, Yatong
Xing, Cheng
Zhang, Hanyu
Wang, Shunda
Dai, Menghua
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-06-29
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Pancreatic cancer is a highly malignant digestive system tumor which is the leading cause of cancer-related deaths.
The basic and clinical research of pancreatic cancer has made great progress in recent years, and kinds of signaling pathways have been found in the tumorigenesis and progression in pancreatic cancer.
The Slit glycoprotein (Slit) and Roundabout receptor (Robo) signaling pathway acts as a neural targeting factor with the axonal remnant, axon guidance, and inhibition of neuronal migration in the nervous system.
In recent years, it has been found that the Slit/Robo signaling pathway has different degrees of expression changes in various tumor cells.
In different tumor cells, the signaling pathway gene expression is different and regulates tumor angiogenesis, cell invasion, metastasis, and nerve infiltration.
Herein, we summarize the mechanisms of the Slit/Robo pathway in the development and progression of pancreatic cancer, in order to have more understanding of the role of Slit/Robo in pancreatic cancer.
American Psychological Association (APA)
Ding, Cheng& Li, Yatong& Xing, Cheng& Zhang, Hanyu& Wang, Shunda& Dai, Menghua. 2020. Research Progress on SlitRobo Pathway in Pancreatic Cancer: Emerging and Promising. Journal of Oncology،Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1188884
Modern Language Association (MLA)
Ding, Cheng…[et al.]. Research Progress on SlitRobo Pathway in Pancreatic Cancer: Emerging and Promising. Journal of Oncology No. 2020 (2020), pp.1-7.
https://search.emarefa.net/detail/BIM-1188884
American Medical Association (AMA)
Ding, Cheng& Li, Yatong& Xing, Cheng& Zhang, Hanyu& Wang, Shunda& Dai, Menghua. Research Progress on SlitRobo Pathway in Pancreatic Cancer: Emerging and Promising. Journal of Oncology. 2020. Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1188884
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1188884