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Extracellular Vesicles Involvement in the Modulation of the Glioblastoma Environment
Joint Authors
Lanuti, Paola
Ciccocioppo, Fausta
Marchisio, Marco
Miscia, Sebastiano
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-01-28
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Glioblastoma (GBM) is the most deadly primary brain tumour and is a paradigmatic example of heterogeneous cancer.
Although expanding data propose the phenotypic plasticity exhibited by glioblastoma cells, as a critical feature involved in the tumour development and posttherapy recurrence, the central machinery responsible for their aggressiveness remains elusive.
Despite decades of research, the complex biology of the glioblastoma is still unknown.
Progress in genetic and epigenetic discoveries has improved diagnostic classification, prognostic information, and therapeutic planning.
In the complex model of intercellular signalling, several studies have shown that extracellular vesicles have a key role in the intercellular communication among GBM cells and the tumour microenvironment modulation.
The purpose of this review is to summarize the role of the EV-mediated intercellular crosstalk in the glioblastoma physiopathology.
American Psychological Association (APA)
Ciccocioppo, Fausta& Lanuti, Paola& Marchisio, Marco& Miscia, Sebastiano. 2020. Extracellular Vesicles Involvement in the Modulation of the Glioblastoma Environment. Journal of Oncology،Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1188925
Modern Language Association (MLA)
Ciccocioppo, Fausta…[et al.]. Extracellular Vesicles Involvement in the Modulation of the Glioblastoma Environment. Journal of Oncology No. 2020 (2020), pp.1-8.
https://search.emarefa.net/detail/BIM-1188925
American Medical Association (AMA)
Ciccocioppo, Fausta& Lanuti, Paola& Marchisio, Marco& Miscia, Sebastiano. Extracellular Vesicles Involvement in the Modulation of the Glioblastoma Environment. Journal of Oncology. 2020. Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1188925
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1188925