Limitations of Systemic Oncological Therapy in Breast Cancer Patients with Chronic Kidney Disease

Joint Authors

Bednarek, Anna
Mykała-Cieśla, Joanna
Pogoda, Katarzyna
Jagiełło-Gruszfeld, Agnieszka
Kunkiel, Michał
Winder, Mateusz
Chudek, Jerzy

Source

Journal of Oncology

Issue

Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-11, 11 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2020-05-18

Country of Publication

Egypt

No. of Pages

11

Main Subjects

Diseases
Medicine

Abstract EN

Breast cancer is the most common malignancy, affecting middle-age and older women frequently suffering from other chronic diseases, including chronic kidney disease.

The risk of breast cancer development in women on renal replacement therapy (peritoneal dialysis and haemodialysis) is higher than in the general population.

Chronic kidney disease does not limit surgical treatment or radiotherapy; however, it affects the pharmacokinetics of drugs used in the systematic treatment to a different extent, increasing their toxicity and the risk of adverse drug reactions.

This article summarizes the current knowledge (published studies accessed through PUBMED) on drugs used in chemotherapy, hormone therapy, anti-HER2 drugs, CDK4/6 inhibitors, PARP inhibitors, and immune therapy in breast cancer patients undergoing dialysis.

We discuss the data, the optimal choice of the chemotherapeutic protocol, and the administration of drugs in a specific time relation to the haemodialysis session to ensure the most effective and safe treatment to breast cancer patients.

American Psychological Association (APA)

Bednarek, Anna& Mykała-Cieśla, Joanna& Pogoda, Katarzyna& Jagiełło-Gruszfeld, Agnieszka& Kunkiel, Michał& Winder, Mateusz…[et al.]. 2020. Limitations of Systemic Oncological Therapy in Breast Cancer Patients with Chronic Kidney Disease. Journal of Oncology،Vol. 2020, no. 2020, pp.1-11.
https://search.emarefa.net/detail/BIM-1189072

Modern Language Association (MLA)

Bednarek, Anna…[et al.]. Limitations of Systemic Oncological Therapy in Breast Cancer Patients with Chronic Kidney Disease. Journal of Oncology No. 2020 (2020), pp.1-11.
https://search.emarefa.net/detail/BIM-1189072

American Medical Association (AMA)

Bednarek, Anna& Mykała-Cieśla, Joanna& Pogoda, Katarzyna& Jagiełło-Gruszfeld, Agnieszka& Kunkiel, Michał& Winder, Mateusz…[et al.]. Limitations of Systemic Oncological Therapy in Breast Cancer Patients with Chronic Kidney Disease. Journal of Oncology. 2020. Vol. 2020, no. 2020, pp.1-11.
https://search.emarefa.net/detail/BIM-1189072

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1189072