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Development of MicroRNAs as Potential Therapeutics against Cancer
Joint Authors
Poh, Chit Laa
Abd-Aziz, Noraini
Kamaruzman, Nur Izyani
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-07-15
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
MicroRNAs (miRNAs) are small noncoding RNAs that function at the posttranscriptional level in the cellular regulation process.
miRNA expression exerts vital effects on cell growth such as cell proliferation and survival.
In cancers, miRNAs have been shown to initiate carcinogenesis, where overexpression of oncogenic miRNAs (oncomiRs) or reduced expression of tumor suppressor miRNAs has been reported.
In this review, we discuss the involvement of miRNAs in tumorigenesis, the role of synthetic miRNAs as either mimics or antagomirs to overcome cancer growth, miRNA delivery, and approaches to enhance their therapeutic potentials.
American Psychological Association (APA)
Abd-Aziz, Noraini& Kamaruzman, Nur Izyani& Poh, Chit Laa. 2020. Development of MicroRNAs as Potential Therapeutics against Cancer. Journal of Oncology،Vol. 2020, no. 2020, pp.1-14.
https://search.emarefa.net/detail/BIM-1189094
Modern Language Association (MLA)
Abd-Aziz, Noraini…[et al.]. Development of MicroRNAs as Potential Therapeutics against Cancer. Journal of Oncology No. 2020 (2020), pp.1-14.
https://search.emarefa.net/detail/BIM-1189094
American Medical Association (AMA)
Abd-Aziz, Noraini& Kamaruzman, Nur Izyani& Poh, Chit Laa. Development of MicroRNAs as Potential Therapeutics against Cancer. Journal of Oncology. 2020. Vol. 2020, no. 2020, pp.1-14.
https://search.emarefa.net/detail/BIM-1189094
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1189094