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The Emerging Role of MicroRNAs in Breast Cancer
Joint Authors
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-07-03
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Breast cancer (BC) is the most common malignancy in women.
Due to BC heterogeneity, complexity, and metastasis, many BC patients do not successfully respond to therapies.
The effective management of BC depends on early diagnosis and monitoring of drug response.
Therefore, identifying new biomarkers for the diagnosis, prognosis, and development of new drugs is urgently required.
Dysregulation of microRNAs (miRNAs) participates in the tumorigenesis and progression of cancers, especially breast cancer (BC).
Several studies demonstrated that miRNAs could perform their function as oncogenes or tumor suppressors.
This review describes recent progress on the role of microRNAs in the diagnosis, prognosis, hallmark, and treatment of BC.
According to a recent literature survey, miRNAs play a pivotal role in the regulation of hallmarks of cancer, such as proliferation, apoptosis, invasion, metastasis, and tumor stemness.
Many miRNAs are potential biomarkers for BC for diagnosis, and some are indicators of prognosis.
Moreover, circulating miRNA profiles, as minimally invasive, diagnostic, and prognostic markers, are broadly used in BC therapy, and some miRNAs are good predictors of therapeutic outcomes.
Other miRNAs are involved in overcoming chemoresistance and in increasing BC drug sensitivity.
American Psychological Association (APA)
Yang, Zhiguang& Liu, Zhaoyu. 2020. The Emerging Role of MicroRNAs in Breast Cancer. Journal of Oncology،Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1189173
Modern Language Association (MLA)
Yang, Zhiguang& Liu, Zhaoyu. The Emerging Role of MicroRNAs in Breast Cancer. Journal of Oncology No. 2020 (2020), pp.1-7.
https://search.emarefa.net/detail/BIM-1189173
American Medical Association (AMA)
Yang, Zhiguang& Liu, Zhaoyu. The Emerging Role of MicroRNAs in Breast Cancer. Journal of Oncology. 2020. Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1189173
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1189173