Chemotherapy Options beyond the First Line in HER-Negative Metastatic Breast Cancer
Joint Authors
Lorusso, Vito
Latorre, Agnese
Giotta, Francesco
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-17, 17 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-11-29
Country of Publication
Egypt
No. of Pages
17
Main Subjects
Abstract EN
Despite the recent advances in the biological understanding of breast cancer (BC), chemotherapy still represents a key component in the armamentarium for this disease.
Different agents are available as mono-chemotherapy options in patients with locally advanced or metastatic BC (MBC) who progress after a first- and second-line treatment with anthracyclines and taxanes.
However, no clear indication exists on what the best option is in some populations, such as heavily pretreated, elderly patients, triple-negative BC (TNBC), and those who do not respond to the first-line therapy.
In this article, we summarize available literature evidence on different chemotherapy agents used beyond the first-line, in locally advanced or MBC patients, including rechallenge with anthracyclines and taxanes, antimetabolite and antimicrotubule agents, such as vinorelbine, capecitabine, eribulin, ixabepilone, and the newest developed agents, such as vinflunine, irinotecan, and etirinotecan.
American Psychological Association (APA)
Lorusso, Vito& Latorre, Agnese& Giotta, Francesco. 2020. Chemotherapy Options beyond the First Line in HER-Negative Metastatic Breast Cancer. Journal of Oncology،Vol. 2020, no. 2020, pp.1-17.
https://search.emarefa.net/detail/BIM-1189201
Modern Language Association (MLA)
Lorusso, Vito…[et al.]. Chemotherapy Options beyond the First Line in HER-Negative Metastatic Breast Cancer. Journal of Oncology No. 2020 (2020), pp.1-17.
https://search.emarefa.net/detail/BIM-1189201
American Medical Association (AMA)
Lorusso, Vito& Latorre, Agnese& Giotta, Francesco. Chemotherapy Options beyond the First Line in HER-Negative Metastatic Breast Cancer. Journal of Oncology. 2020. Vol. 2020, no. 2020, pp.1-17.
https://search.emarefa.net/detail/BIM-1189201
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1189201