The Ventilatory and Diffusion Dysfunctions in Obese Patients with and without Obstructive Sleep Apnea-Hypopnea Syndrome
Joint Authors
Ghannouchi, Ines
Kammoun, Rim
Ben Saad, Helmi
Rouatbi, Sonia
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-02-10
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Objective.
To analyze the ventilatory and alveolar-capillary diffusion dysfunctions in case of obesity with or without an OSAS.
Methods.
It is a cross-sectional study of 48 obese adults (23 OSAS and 25 controls).
Anthropometric data (height, weight, and body mass index (BMI)) were collected.
All adults responded to a medical questionnaire and underwent polysomnography or sleep polygraphy for apnea-hypopnea index (AHI) and percentage of desaturation measurements.
The following lung function data were collected: pulmonary flows and volumes, lung transfer factor for carbon monoxide (DLCO), and fraction of exhaled nitric oxide (FeNO).
Results.
Obesity was confirmed for the two groups with a total sample mean value of BMI = 35.06 ± 4.68 kg/m2.
A significant decrease in lung function was noted in patients with OSAS compared with controls.
Indeed, when compared with the control group, the OSAS one had a severe restrictive ventilatory defect (total lung capacity: 93 ± 14 vs.
79 ± 12%), an abnormal DLCO (112 ± 20 vs.
93 ± 22%), and higher bronchial inflammation (18.40 ± 9.20 vs.
31.30 ± 13.60 ppb) (p<0.05).
Conclusion.
Obesity when associated with OSAS increases the severity of pulmonary function and alveolar-capillary diffusion alteration.
This can be explained in part by the alveolar inflammation.
American Psychological Association (APA)
Rouatbi, Sonia& Ghannouchi, Ines& Kammoun, Rim& Ben Saad, Helmi. 2020. The Ventilatory and Diffusion Dysfunctions in Obese Patients with and without Obstructive Sleep Apnea-Hypopnea Syndrome. Journal of Obesity،Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1189268
Modern Language Association (MLA)
Rouatbi, Sonia…[et al.]. The Ventilatory and Diffusion Dysfunctions in Obese Patients with and without Obstructive Sleep Apnea-Hypopnea Syndrome. Journal of Obesity No. 2020 (2020), pp.1-6.
https://search.emarefa.net/detail/BIM-1189268
American Medical Association (AMA)
Rouatbi, Sonia& Ghannouchi, Ines& Kammoun, Rim& Ben Saad, Helmi. The Ventilatory and Diffusion Dysfunctions in Obese Patients with and without Obstructive Sleep Apnea-Hypopnea Syndrome. Journal of Obesity. 2020. Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1189268
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1189268