Ocular Surface Disease Index and Ocular Thermography in Keratoconus Patients
Joint Authors
Langenbucher, Achim
Nagy, Zoltán Zsolt
Eppig, Timo
Németh, Orsolya
Lepper, Sabine
Milioti, Georgia
Abdin, Aladin
Szentmáry, Nóra
Seitz, Berthold
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-02-24
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Purpose.
Keratoconus (KC) has been defined as a “noninflammatory” corneal disease, but recent studies have noted a potential inflammatory origin.
We analysed the Ocular Surface Disease Index (OSDI) and ocular surface temperature (OST) in KC patients compared to controls.
Patients and Methods.
A total of 179 eyes in 90 patients with KC (topographic keratoconus classification 0-1 to 4, age 36.1 ± 12.5 years, 65.9% males) and 82 eyes in 41 controls (age 36.4 ± 12.8 years, 47.6% males) were examined.
The participants completed the OSDI questionnaire and underwent corneal topography, tomography, and thermography.
Additional outcome measures were vision- and discomfort-related OSDI subscores and mean OST at the corneal centre during 10 seconds of sustained eye opening after blinking.
Results.
The OSDI score (31.4 ± 22.4 vs.
17.5 ± 17.9) and vision- (17.7 ± 14.6 vs.
10.5 ± 13.2) and discomfort-related (14.3 ± 10.7 vs.
9.4 ± 10.5) OSDI subscores were significantly higher in KC patients than in controls (p<0.001).
We found no significant difference in the central corneal OST (34.2 ± 0.6°C vs.
34.2 ± 0.7°C; p=0.41) between the two groups (p≥0.22).
The OSDI score and subscores poorly to fairly correlated with the surface asymmetry index (SAI) and surface regularity index (SRI; r > 0.174, p<0.005), but did not correlate with the central corneal OST (r < 0.001).
OST also did not correlate with the SAI, SRI, and central corneal thickness (r ≥ −0.086).
Conclusion.
KC patients had increased OSDI scores and vision- and discomfort-related OSDI subscores without an increase in the OST compared to a normal population.
OSDI score/subscores weakly correlate with SAI and SRI but do not correlate with OST in KC patients or controls.
Vision- and discomfort-related symptoms of KC have to be managed in parallel in ophthalmological practice, but the necessity of anti-inflammatory treatment cannot be verified through ocular thermography.
American Psychological Association (APA)
Németh, Orsolya& Langenbucher, Achim& Eppig, Timo& Lepper, Sabine& Milioti, Georgia& Abdin, Aladin…[et al.]. 2020. Ocular Surface Disease Index and Ocular Thermography in Keratoconus Patients. Journal of Ophthalmology،Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1189298
Modern Language Association (MLA)
Németh, Orsolya…[et al.]. Ocular Surface Disease Index and Ocular Thermography in Keratoconus Patients. Journal of Ophthalmology No. 2020 (2020), pp.1-8.
https://search.emarefa.net/detail/BIM-1189298
American Medical Association (AMA)
Németh, Orsolya& Langenbucher, Achim& Eppig, Timo& Lepper, Sabine& Milioti, Georgia& Abdin, Aladin…[et al.]. Ocular Surface Disease Index and Ocular Thermography in Keratoconus Patients. Journal of Ophthalmology. 2020. Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1189298
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1189298