Age-Related Physiologic Thinning Rate of the Retinal Nerve Fiber Layer in Different Levels of Myopia
Joint Authors
Yun, Sung-Cheol
Sung, Kyung Rim
Jeong, Daun
Jo, Youn Hye
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-01-21
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Purpose.
To investigate the effect of refractive error on the physiologic thinning rate of the retinal nerve fiber layer (RNFL) in healthy eyes.
Materials and Methods.
This study analyzed 223 eyes of 141 healthy subjects followed for more than 5 years and underwent at least five serial spectral domain optical coherence tomography (SD-OCT) examinations.
Longitudinal RNFL measurements were analyzed by linear mixed models incorporating follow-up duration, baseline RNFL thickness, spherical equivalent (SE), age, intraocular pressure, and visual field mean deviation.
Thinning rates were classified according to SE into three groups: nonmyopic (NM; >0 D), mild-to-moderately myopic (MM; >–6 D and ≤0 D), and highly myopic (HM; ≤–6 D).
Results.
The overall slopes of change in RNFL thickness over time in the NM, MM, and HM groups were −0.305 ± 0.128, −0.294 ± 0.068, and −0.208 ± 0.097 μm/yr, respectively.
Slopes of RNFL thickness changes in these groups were −0.514 ± 0.248, −0.520 ± 0.133, and −0.528 ± 0.188 μm/yr, in the superior quadrant; −0.084 ± 0.145, 0.107 ± 0.082, and −0.161 ± 0.112 μm/yr, in the temporal quadrant; −0.807 ± 0.242, −0.794 ± 0.130, and −0.727 ± 0.183 μm/yr, in the inferior quadrant; and 0.160 ± 0.157, 0.118 ± 0.084, and 0.429 ± 0.119 μm/yr, in the nasal quadrant.
Overall and in all four quadrants, there was no significant difference in the rate of RNFL thickness change among the three groups.
Conclusions.
Refractive error did not affect the physiologic thinning rate of RNFL when assessed by SD OCT.
American Psychological Association (APA)
Jeong, Daun& Sung, Kyung Rim& Jo, Youn Hye& Yun, Sung-Cheol. 2020. Age-Related Physiologic Thinning Rate of the Retinal Nerve Fiber Layer in Different Levels of Myopia. Journal of Ophthalmology،Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1189311
Modern Language Association (MLA)
Jeong, Daun…[et al.]. Age-Related Physiologic Thinning Rate of the Retinal Nerve Fiber Layer in Different Levels of Myopia. Journal of Ophthalmology No. 2020 (2020), pp.1-6.
https://search.emarefa.net/detail/BIM-1189311
American Medical Association (AMA)
Jeong, Daun& Sung, Kyung Rim& Jo, Youn Hye& Yun, Sung-Cheol. Age-Related Physiologic Thinning Rate of the Retinal Nerve Fiber Layer in Different Levels of Myopia. Journal of Ophthalmology. 2020. Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1189311
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1189311