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Incidence of Endophthalmitis after Intravitreal Anti-Vascular Endothelial Growth Factor Injections in an Operating Room in China
Joint Authors
Zhou, Haiying
Huang, Yao
She, Haicheng
Chen, Yanyun
Wei, Wenbin
Vavvas, Demetrios G.
Ntentakis, Dimitrios P.
Shi, Xiangyu
Li, Lei
Zhang, Feng
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-11-16
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Purpose.
To evaluate the rate of presumed endophthalmitis (EO) after intravitreal anti-vascular endothelial growth factor (anti-VEGF) injections performed in an operating room (OR) under sterile conditions in mainland China.
Methods.
Retrospective single-center study between September 2012 and December 2017 at Beijing Tongren Eye Center, Beijing, China.
Intravitreal injection database was reviewed.
All anti-VEGF injections were performed using a standardized sterile technique in an OR.
Injection protocols included antibiotics for 3 days pre-injection, topical 5% povidone-iodine rinsing before the procedure, and post-injection antibiotics for 3 days.
Results.
A total of 37,830 intravitreal injections were performed at Beijing Tongren Eye Center.
Three cases were managed as presumed EO (0.0079%).
Positive cultures were documented in 2 of 3 cases.
EO incidence following ranibizumab and conbercept administration was 0.0088% (3 in 33,930) and 0% (0 in 3,900), respectively.
No significant difference was detected between the two drugs (P=0.745).
Conclusions.
Very low EO rates were seen in mainland China using a standardized sterile technique in an OR.
However, EO could not be completely avoided.
American Psychological Association (APA)
Chen, Yanyun& Wei, Wenbin& Vavvas, Demetrios G.& Zhang, Feng& She, Haicheng& Zhou, Haiying…[et al.]. 2020. Incidence of Endophthalmitis after Intravitreal Anti-Vascular Endothelial Growth Factor Injections in an Operating Room in China. Journal of Ophthalmology،Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1189464
Modern Language Association (MLA)
Chen, Yanyun…[et al.]. Incidence of Endophthalmitis after Intravitreal Anti-Vascular Endothelial Growth Factor Injections in an Operating Room in China. Journal of Ophthalmology No. 2020 (2020), pp.1-6.
https://search.emarefa.net/detail/BIM-1189464
American Medical Association (AMA)
Chen, Yanyun& Wei, Wenbin& Vavvas, Demetrios G.& Zhang, Feng& She, Haicheng& Zhou, Haiying…[et al.]. Incidence of Endophthalmitis after Intravitreal Anti-Vascular Endothelial Growth Factor Injections in an Operating Room in China. Journal of Ophthalmology. 2020. Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1189464
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1189464