Normative Values of Retinal Nerve Fibre Layer Thickness and Optic Nerve Head Parameters and Their Association with Visual Function in an African Population
Joint Authors
Kyei, Samuel
Abu, Emmanuel Kwasi
Boadi-Kusi, Samuel Bert
Morny, Enyam Komla Amewuho
Ocansey, Stephen
Owusu-Ansah, Andrew
Mensah, Shadrack
Oduro-Boateng, John
Kojo, Rene Abalo
Amoah-Smith, Obed
Darko-Takyi, Charles
Abraham, Carl Halladay
Appiah Nyamekye, Benjamin
Ilechie, Alex Azuka
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-02-11
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
Purpose.
To determine normative values of retinal nerve fibre layer thickness (RNFL) and optic nerve head (ONH) parameters and their association with routine clinical tests such as refractive error (RE), stereoacuity (SA), and contrast sensitivity (CS) in an African population.
Methods.
In a cross-sectional observational study, 100 normal subjects aged 20 to 78 years were evaluated using the Cirrus HD-OCT 5000 and matched with 200 glaucoma patients.
Results.
Average (±SD) RNFL thickness for normal subjects was found to be 102.37 ± 7.45 (range, 82–119 microns) compared with 90.74 ± 14.50 found for glaucoma subjects.
Females had higher average RNFL values (104.84 ± 6.90) compared with males (99.80 ± 7.18).
Significant associations were calculated between quadrant RNFL thickness and SA, SE, and CS (all p<0.05).
The mean cup to disc ratio (CDR) was 0.49 ± 0.12, and mean optic disc area (DA) was 2.08 mm2 ± 0.40.
Smaller DA was recorded for participants aged 60+ years (1.86 ± 0.25), followed by 40–59 age group (2.01 ± 0.41) and then 20–39 age group (2.19 ± 0.41).
Significant associations were calculated between SA and ONH parameters, except rim area (all p<0.01), and RE was significantly associated with DA and average CDR (all p<0.05).
Conclusion.
RNFL thickness in healthy black Ghanaian population was significantly higher than that reported in other races.
The values and associations reported in this study can inform clinical decision on the normal variation in RNFL and optic disc parameters.
American Psychological Association (APA)
Ocansey, Stephen& Abu, Emmanuel Kwasi& Owusu-Ansah, Andrew& Mensah, Shadrack& Oduro-Boateng, John& Kojo, Rene Abalo…[et al.]. 2020. Normative Values of Retinal Nerve Fibre Layer Thickness and Optic Nerve Head Parameters and Their Association with Visual Function in an African Population. Journal of Ophthalmology،Vol. 2020, no. 2020, pp.1-14.
https://search.emarefa.net/detail/BIM-1189630
Modern Language Association (MLA)
Ocansey, Stephen…[et al.]. Normative Values of Retinal Nerve Fibre Layer Thickness and Optic Nerve Head Parameters and Their Association with Visual Function in an African Population. Journal of Ophthalmology No. 2020 (2020), pp.1-14.
https://search.emarefa.net/detail/BIM-1189630
American Medical Association (AMA)
Ocansey, Stephen& Abu, Emmanuel Kwasi& Owusu-Ansah, Andrew& Mensah, Shadrack& Oduro-Boateng, John& Kojo, Rene Abalo…[et al.]. Normative Values of Retinal Nerve Fibre Layer Thickness and Optic Nerve Head Parameters and Their Association with Visual Function in an African Population. Journal of Ophthalmology. 2020. Vol. 2020, no. 2020, pp.1-14.
https://search.emarefa.net/detail/BIM-1189630
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1189630