![](/images/graphics-bg.png)
Causes and Clinical Impact of Loss to Follow-Up in Patients with Proliferative Diabetic Retinopathy
Joint Authors
Abdelmotaal, Hazem
Abdelazeem, Khaled
Ibrahim, Walid
Sharaf, Mohamed
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-02-08
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Purpose.
This study determined the clinical impact and causes of loss to follow-up (LTFU) from the patients’ perspective in individuals with proliferative diabetic retinopathy (PDR) who received panretinal photocoagulation (PRP) and/or intravitreal injections (IVIs) of antivascular endothelial growth factor (VEGF).
Methods.
This prospective cohort study included 467 patients with PDR who received PRP and/or IVIs of anti-VEGF between May 2013 and June 2018.
LTFU was defined as missing any follow-up visit for any interval exceeding 6 months, provided that patients eventually resumed care.
Main outcome measures include rates and causes of LTFU.
Results.
A total of 391 patients (83.7%) were followed up, and 76 patients (16.3%) were LTFU over the study period.
Rates of LTFU decreased with age (P=0.005).
Questionnaire analysis conducted for patients’ LTFU showed a significant positive correlation between best corrected visual activity (BCVA) loss and patient’s lack of trust and satisfaction with treatment (rs = 0.458, P<0.001).
There was also a significant positive correlation between treatment unaffordability and number of IVIs of anti-VEGF (rs = 0.55, P<0.001) and lack of social support and age (rs = 0.39, P<0.001).
Conclusions.
LTFU threatens vision in PDR patients receiving PRP and/or IVIs of anti-VEGF.
Possibly, patient-specific LTFU causes should be addressed before treatment in order to minimize the risk of LTFU.
The clinical trial is registered with NCT04018326 (trial registration: ClinicalTrials.gov Identifier: NCT04018326, 10th of July 2019 “Retrospectively registered”).
American Psychological Association (APA)
Abdelmotaal, Hazem& Ibrahim, Walid& Sharaf, Mohamed& Abdelazeem, Khaled. 2020. Causes and Clinical Impact of Loss to Follow-Up in Patients with Proliferative Diabetic Retinopathy. Journal of Ophthalmology،Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1189693
Modern Language Association (MLA)
Abdelmotaal, Hazem…[et al.]. Causes and Clinical Impact of Loss to Follow-Up in Patients with Proliferative Diabetic Retinopathy. Journal of Ophthalmology No. 2020 (2020), pp.1-8.
https://search.emarefa.net/detail/BIM-1189693
American Medical Association (AMA)
Abdelmotaal, Hazem& Ibrahim, Walid& Sharaf, Mohamed& Abdelazeem, Khaled. Causes and Clinical Impact of Loss to Follow-Up in Patients with Proliferative Diabetic Retinopathy. Journal of Ophthalmology. 2020. Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1189693
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1189693