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Retinal Nerve Fibre Layer Thinning in Patients with Thalassaemia, Iron Deficiency Anaemia, and Anaemia of Chronic Diseases
Joint Authors
Datta, Suhana
Baidya, Krishnapada
Banerjee, Madhumita
Mahapatra, Somnath
Mukherjee, Sudeb
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-11-18
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Purpose.
Retinal nerve fibre layer (RNFL) is a sensitive structure, which is affected by anaemia due to hypoxia.
A timely detection of RNFL thinning may aid preventing devastating complications.
Optical coherence tomography (OCT) measures RNFL thinning with accuracy and helps in detecting thinning of the retinal layer in anaemic patients.
This study was destined to evaluate thinning of RNFL in anaemic patients and their correlation with the haemoglobin level.
Methods.
It was a prospective comparative study.
Total of 151 patients were included in this study.
Patients with retinal diseases were excluded from this study.
After initial evaluation, haematological and ophthalmological parameters were measured.
RNFL was measured with OCT and corroborated with the Hb level and analysed accordingly.
EPI and SPSS softwares were used for detail analysis and the correlation between RNFL thinning and the Hb level.
Initially, each eye was separately assigned a value (0, 1, and 2) (normal, borderline, and abnormal, respectively) as per the severity of thinning, and then, the sum of the scores of both eyes were considered as a separate variable, and a multiple linear regression analysis was performed with the independent variables.
Results.
RNFL thinning was found to be significant in each group of patients.
There was a strong correlation of RNFL thinning with degree of anaemia.
Conclusions.
Thalassaemia, iron deficiency anaemia, and anaemia of chronic diseases are associated with the significant damage to RNFL.
Degree of anaemia is the most important parameter for such thinning of the RNFL layer.
American Psychological Association (APA)
Datta, Suhana& Baidya, Krishnapada& Banerjee, Madhumita& Mahapatra, Somnath& Mukherjee, Sudeb. 2020. Retinal Nerve Fibre Layer Thinning in Patients with Thalassaemia, Iron Deficiency Anaemia, and Anaemia of Chronic Diseases. Journal of Ophthalmology،Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1189867
Modern Language Association (MLA)
Datta, Suhana…[et al.]. Retinal Nerve Fibre Layer Thinning in Patients with Thalassaemia, Iron Deficiency Anaemia, and Anaemia of Chronic Diseases. Journal of Ophthalmology No. 2020 (2020), pp.1-7.
https://search.emarefa.net/detail/BIM-1189867
American Medical Association (AMA)
Datta, Suhana& Baidya, Krishnapada& Banerjee, Madhumita& Mahapatra, Somnath& Mukherjee, Sudeb. Retinal Nerve Fibre Layer Thinning in Patients with Thalassaemia, Iron Deficiency Anaemia, and Anaemia of Chronic Diseases. Journal of Ophthalmology. 2020. Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1189867
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1189867