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The Influence of Antenatal Oral Iron and Folic Acid Side Effects on Supplementation Duration in Low-Resource Rural Kenya: A Cross-Sectional Study
Joint Authors
Oiye, Shadrack
Juma, Margaret
Konyole, Silvenus
Adan, Fatuma
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-05-11
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background.
Undesirable effects of a daily regimen of iron and folic acid ingested jointly (iron-folate) are potential disincentives to optimal antenatal supplementation.
We intended to profile antenatal iron-folate side effects and elucidate their influence on supplementation duration in low-resource rural Kenya.
Methods.
This was a cross-sectional descriptive study of randomly selected postnatal mothers of under-five-year-old children.
Using a modified WHO Safe Motherhood Assessment standard questionnaire, they recalled the total number of days of antenatal iron-folate intake and the attendant supplement-attributed undesirable experiences.
The analyses considered only participants who ingested the supplements in their immediate last pregnancies (n=277).
Results.
About half of the study participants reported at least a side effect and a mean of 2.4 (SD 1.5) effects per person in the entire pregnancy period.
Most common reported effects were chest pains (31.8%), constipation (28.5%), severe stomach pains (11.6%), and diarrhoea (11.6%).
Mothers who reported at least a side effect ingested the supplements for ten days less compared to those who did not experience any effect (p=0.03); and a greater proportion of the former were primigravida (p=0.02) and used combined form of iron and folic acid (p=0.003).
In a multivariate analysis, significant correlations with supplementation compliance (ingestion for 90+ days) were found only for nausea and severe stomach pain experiences (r=−0.1, p=0.04; r=0.2, p=0.01, resp.).
Conclusions.
The commonness of undesirable experiences attributed to daily ingestion of 60 mg iron and 0.4 mg folic acid and their deterrence to longer supplementation durations suggest the need for considering a weekly intermittent regimen for some antenatal women in such set-ups.
Our study demonstrated that potentially, more counselling on nausea as a side effect might be critical in advancing iron-folate supplementation compliance.
American Psychological Association (APA)
Oiye, Shadrack& Juma, Margaret& Konyole, Silvenus& Adan, Fatuma. 2020. The Influence of Antenatal Oral Iron and Folic Acid Side Effects on Supplementation Duration in Low-Resource Rural Kenya: A Cross-Sectional Study. Journal of Pregnancy،Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1190027
Modern Language Association (MLA)
Oiye, Shadrack…[et al.]. The Influence of Antenatal Oral Iron and Folic Acid Side Effects on Supplementation Duration in Low-Resource Rural Kenya: A Cross-Sectional Study. Journal of Pregnancy No. 2020 (2020), pp.1-7.
https://search.emarefa.net/detail/BIM-1190027
American Medical Association (AMA)
Oiye, Shadrack& Juma, Margaret& Konyole, Silvenus& Adan, Fatuma. The Influence of Antenatal Oral Iron and Folic Acid Side Effects on Supplementation Duration in Low-Resource Rural Kenya: A Cross-Sectional Study. Journal of Pregnancy. 2020. Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1190027
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1190027