Fibrosis following Acute Skeletal Muscle Injury: Mitigation and Reversal Potential in the Clinic
Joint Authors
Gardner, Tyler
Kenter, Keith
Li, Yong
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-09-01
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Skeletal muscle injuries occur often in athletics and in daily life.
In minor injuries, muscles are able to regenerate completely and recover their functional capabilities.
However, in the case of severe injuries, the injured muscle cannot recover to a functional level because of the formation of fibrous scar tissue.
The physical barrier of scars is significantly challenged in both research and clinical treatment.
Fibrous scar tissue not only limits cells’ migration, but also contributes to normal tissue biomechanical properties.
This scar formation creates an unsuitable environment for tissue structure resulting in frequent pain.
Antifibrosis treatment is one of the major strategies used to augment muscle regeneration and accelerate its functional recovery.
This review will discuss the currently available methods for improving muscle regeneration with a specific focus on antifibrosis applications.
We also discussed several novel hypotheses and clinical applications in muscle fibrosis treatment currently in practice.
American Psychological Association (APA)
Gardner, Tyler& Kenter, Keith& Li, Yong. 2020. Fibrosis following Acute Skeletal Muscle Injury: Mitigation and Reversal Potential in the Clinic. Journal of Sports Medicine،Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1190764
Modern Language Association (MLA)
Gardner, Tyler…[et al.]. Fibrosis following Acute Skeletal Muscle Injury: Mitigation and Reversal Potential in the Clinic. Journal of Sports Medicine No. 2020 (2020), pp.1-7.
https://search.emarefa.net/detail/BIM-1190764
American Medical Association (AMA)
Gardner, Tyler& Kenter, Keith& Li, Yong. Fibrosis following Acute Skeletal Muscle Injury: Mitigation and Reversal Potential in the Clinic. Journal of Sports Medicine. 2020. Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1190764
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1190764