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Management of Iron Overload in Resource Poor Nations: A Systematic Review of Phlebotomy and Natural Chelators
Joint Authors
Amadi, Cecilia Nwadiuto
Frazzoli, Chiara
Orisakwe, Orish Ebere
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-01-27
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
Iron is an essential element and the most abundant trace metal in the body involved in oxygen transport and oxygen sensing, electron transfer, energy metabolism, and DNA synthesis.
Excess labile and unchelated iron can catalyze the formation of tissue-damaging radicals and induce oxidative stress.
English abstracts were identified in PubMed and Google Scholar using multiple and various search terms based on defined inclusion and exclusion criteria.
Full-length articles were selected for systematic review, and secondary and tertiary references were developed.
Although bloodletting or phlebotomy remains the gold standard in the management of iron overload, this systematic review is an updated account of the pitfalls of phlebotomy and classical synthetic chelators with scientific justification for the use of natural iron chelators of dietary origin in resource-poor nations.
American Psychological Association (APA)
Orisakwe, Orish Ebere& Amadi, Cecilia Nwadiuto& Frazzoli, Chiara. 2020. Management of Iron Overload in Resource Poor Nations: A Systematic Review of Phlebotomy and Natural Chelators. Journal of Toxicology،Vol. 2020, no. 2020, pp.1-14.
https://search.emarefa.net/detail/BIM-1190892
Modern Language Association (MLA)
Orisakwe, Orish Ebere…[et al.]. Management of Iron Overload in Resource Poor Nations: A Systematic Review of Phlebotomy and Natural Chelators. Journal of Toxicology No. 2020 (2020), pp.1-14.
https://search.emarefa.net/detail/BIM-1190892
American Medical Association (AMA)
Orisakwe, Orish Ebere& Amadi, Cecilia Nwadiuto& Frazzoli, Chiara. Management of Iron Overload in Resource Poor Nations: A Systematic Review of Phlebotomy and Natural Chelators. Journal of Toxicology. 2020. Vol. 2020, no. 2020, pp.1-14.
https://search.emarefa.net/detail/BIM-1190892
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1190892