A Comprehensive Method for Accurate Strain Distribution Measurement of Cell Substrate Subjected to Large Deformation
Joint Authors
Zhou, Rong
Zou, Yuanwen
He, Hong
Huang, Xuejin
Li, Jinchuan
Source
Journal of Healthcare Engineering
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-01-08
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Cell mechanical stretching in vitro is a fundamental technique commonly used in cardiovascular mechanobiology research.
Accordingly, it is crucial to measure the accurate strain field of cell substrate under different strains.
Digital image correlation (DIC) is a widely used measurement technique, which is able to obtain the accurate displacement and strain distribution.
However, the traditional DIC algorithm used in digital image correlation engine (DICe) cannot obtain accurate result when utilized in large strain measurement.
In this paper, an improved method aiming to acquire accurate strain distribution of substrate in large deformation was proposed, to evaluate the effect and accuracy, based on numerical experiments.
The results showed that this method was effective and highly accurate.
Then, we carried out uniaxial substrate stretching experiments and applied our method to measure strain distribution of the substrate.
The proposed method could obtain accurate strain distribution of substrate film during large stretching, which would allow researchers to adequately describe the response of cells to different strains of substrate.
American Psychological Association (APA)
He, Hong& Zhou, Rong& Zou, Yuanwen& Huang, Xuejin& Li, Jinchuan. 2018. A Comprehensive Method for Accurate Strain Distribution Measurement of Cell Substrate Subjected to Large Deformation. Journal of Healthcare Engineering،Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1191226
Modern Language Association (MLA)
He, Hong…[et al.]. A Comprehensive Method for Accurate Strain Distribution Measurement of Cell Substrate Subjected to Large Deformation. Journal of Healthcare Engineering No. 2018 (2018), pp.1-10.
https://search.emarefa.net/detail/BIM-1191226
American Medical Association (AMA)
He, Hong& Zhou, Rong& Zou, Yuanwen& Huang, Xuejin& Li, Jinchuan. A Comprehensive Method for Accurate Strain Distribution Measurement of Cell Substrate Subjected to Large Deformation. Journal of Healthcare Engineering. 2018. Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1191226
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1191226