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Nonmotile Single-Cell Migration as a Random Walk in Nonuniformity: The “Extreme Dumping Limit” for Cell-to-Cell Communications
Joint Authors
Haidar, Ziyad S.
Panotopoulos, Grigorios P.
Aguayo, Sebastian
Source
Journal of Healthcare Engineering
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-11-25
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
In the present work, we model single-cell movement as a random walk in an external potential observed within the extreme dumping limit, which we define herein as the extreme nonuniform behavior observed for cell responses and cell-to-cell communications.
Starting from the Newton–Langevin equation of motion, we solve the corresponding Fokker–Planck equation to compute higher moments of the displacement of the cell, and then we build certain quantities that can be measurable experimentally.
We show that, each time, the dynamics depend on the external force applied, leading to predictions distinct from the standard results of a free Brownian particle.
Our findings demonstrate that cell migration viewed as a stochastic process is still compatible with biological and experimental observations without the need to rely on more complicated or sophisticated models proposed previously in the literature.
American Psychological Association (APA)
Panotopoulos, Grigorios P.& Aguayo, Sebastian& Haidar, Ziyad S.. 2018. Nonmotile Single-Cell Migration as a Random Walk in Nonuniformity: The “Extreme Dumping Limit” for Cell-to-Cell Communications. Journal of Healthcare Engineering،Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1191425
Modern Language Association (MLA)
Panotopoulos, Grigorios P.…[et al.]. Nonmotile Single-Cell Migration as a Random Walk in Nonuniformity: The “Extreme Dumping Limit” for Cell-to-Cell Communications. Journal of Healthcare Engineering No. 2018 (2018), pp.1-8.
https://search.emarefa.net/detail/BIM-1191425
American Medical Association (AMA)
Panotopoulos, Grigorios P.& Aguayo, Sebastian& Haidar, Ziyad S.. Nonmotile Single-Cell Migration as a Random Walk in Nonuniformity: The “Extreme Dumping Limit” for Cell-to-Cell Communications. Journal of Healthcare Engineering. 2018. Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1191425
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1191425