Synovial Macrophages in Rheumatoid Arthritis: The Past, Present, and Future
Joint Authors
Wei, Wei
Tu, Jiajie
Wang, Xinming
Gong, Xun
Hong, Wenming
Han, Dafei
Fang, Yilong
Guo, Yawei
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-04-13
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
The ontogeny of macrophages in most organs has already been established.
Owing to the limited number and inaccessibility of synovial macrophages (SMs), the origin of SMs has not been fully elucidated.
Previous studies suggested that SMs have two major origins, namely, tissue-resident and monocyte-derived SMs.
However, no systematic analysis to identify SM ontology in either physiological or pathological conditions has been available to date.
In this review, we summarize relevant studies on the two main origins of SMs in rheumatoid arthritis (RA) and forecast the future research directions for this field.
Furthermore, we discuss the current state of RA therapy that is based on targeting different SM subsets.
American Psychological Association (APA)
Tu, Jiajie& Wang, Xinming& Gong, Xun& Hong, Wenming& Han, Dafei& Fang, Yilong…[et al.]. 2020. Synovial Macrophages in Rheumatoid Arthritis: The Past, Present, and Future. Mediators of Inflammation،Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1191509
Modern Language Association (MLA)
Tu, Jiajie…[et al.]. Synovial Macrophages in Rheumatoid Arthritis: The Past, Present, and Future. Mediators of Inflammation No. 2020 (2020), pp.1-8.
https://search.emarefa.net/detail/BIM-1191509
American Medical Association (AMA)
Tu, Jiajie& Wang, Xinming& Gong, Xun& Hong, Wenming& Han, Dafei& Fang, Yilong…[et al.]. Synovial Macrophages in Rheumatoid Arthritis: The Past, Present, and Future. Mediators of Inflammation. 2020. Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1191509
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1191509