Pain Mechanism in Rheumatoid Arthritis: From Cytokines to Central Sensitization
Joint Authors
Fan, Danping
Cao, Yanting
Yin, Yiqing
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-09-12
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Pain is the most common symptom in patients with rheumatoid arthritis (RA).
Although in recent years, through the implementation of targeted treatment and the introduction of disease-modifying antirheumatic drugs (DMARDs), the treatment of RA patients has made a significant progress, a large proportion of patients still feel pain.
Finding appropriate treatment to alleviate the pain is very important for RA patients.
Current research showed that, in addition to inflammation, RA pain involves peripheral sensitization and abnormalities in the central nervous system (CNS) pain regulatory mechanisms.
This review summarized the literature on pain mechanisms of RA published in recent years.
A better understanding of pain mechanisms will help to develop new analgesic targets and deploy new and existing therapies.
American Psychological Association (APA)
Cao, Yanting& Fan, Danping& Yin, Yiqing. 2020. Pain Mechanism in Rheumatoid Arthritis: From Cytokines to Central Sensitization. Mediators of Inflammation،Vol. 2020, no. 2020, pp.1-11.
https://search.emarefa.net/detail/BIM-1191559
Modern Language Association (MLA)
Cao, Yanting…[et al.]. Pain Mechanism in Rheumatoid Arthritis: From Cytokines to Central Sensitization. Mediators of Inflammation No. 2020 (2020), pp.1-11.
https://search.emarefa.net/detail/BIM-1191559
American Medical Association (AMA)
Cao, Yanting& Fan, Danping& Yin, Yiqing. Pain Mechanism in Rheumatoid Arthritis: From Cytokines to Central Sensitization. Mediators of Inflammation. 2020. Vol. 2020, no. 2020, pp.1-11.
https://search.emarefa.net/detail/BIM-1191559
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1191559